pirimiphos-methyl

Identification (Source:EPA,EU)

ID 235
Name pirimiphos-methyl
CAS 29232-93-7
IUPAC
Inchi InChI=1S/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3
CIPAC 239
EPA Code 108102
Formula C11H20N3O3PS
SMILES S=P(OC)(OC)Oc1nc(nc(c1)C)N(CC)CC
Status Approved

Classification

Mode of Action Broad-spectrum with contact and respiratory action. Acetylcholinesterase (AChE) inhibitor.
Pesticide Type Insecticide, Acaricide
Chemical Group Organophosphate
Classification organothiophosphate insecticides
heterocyclic organothiophosphate insecticides
pyrimidine organothiophosphate insecticides
organothiophosphate acaricides

Properties (Source:PubChem)

Molecular Weight 305.33
Physical State Straw coloured liquid
AlogP 2.114
H-Bond Donor 0
H-Bond Acceptor 7
Surface Area 313.73
Polar Surface Area 98.61

Structure



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3D similarity method

2D similarity method

Compound Database



Bioactivity Database

KEGG (5,928)

PDB (7,072)


Similarity Threshold

Ecotoxicology (Source:PPDB,IPM)

Species Method Study Time Dose Type Value
Algae Acute 72 hour EC50, growth 1.0 mg l-1
Aquatic invertebrates Acute 48 hour EC50 0.00021 mg l-1
Aquatic invertebrates Chronic 21 day NOEC 0.00008 mg l-1
Birds Acute LD50 > 1695 mg kg-1
Fish Acute 96 hour LC50 0.404 mg l-1
Fish Chronic 21 day NOEC 0.023 mg l-1
Honeybees Acute 48 hour LD50 > 0.22 μg bee-1
Mammals Acute oral LD50 1414 mg kg-1
Mammals Short term dietary NOEL 0.5 mg kg-1
Sediment dwelling organisms Acute 96 hour LC50 0.039 mg l-1
Bio-concentration factor CT50 Not available days
Bio-concentration factor BCF 741

Related targets

Target Name RScore (About this table)
Acetylcholinesterase 316(2,5,9,46) Details
cholinesterase 130(1,2,3,15) Details
glutathione S transferase 44(0,1,2,9) Details
albumin 41(0,1,1,11) Details
CARB 33(0,1,1,3) Details
tripeptidyl aminopeptidase 31(0,1,1,1) Details
proline endopeptidase 31(0,1,1,1) Details
aminopeptidase 31(0,1,1,1) Details
leucyl aminopeptidases 31(0,1,1,1) Details
cathepsin D 31(0,1,1,1) Details
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