Protein Information

Name p38
Synonyms AIMP 2; p38; AIMP2; JTV 1; JTV1; JTV1 gene; JTV1 protein; Multisynthetase complex auxiliary component p38…

Compound Information

Name OCH
CAS 2,3,4,4,5,5,6,6-octachloro-2-cyclohexen-1-one

Reference List

PubMed Abstract RScore(About this table)
10679516 Ito T, Kozawa O, Tanabe K, Niwa M, Matsuno H, Sakai N, Ito H, Kato K, Uematsu T: p38 MAP kinase is required for vasopressin-stimulated HSP27 induction in aortic smooth muscle cells. Hypertension. 2000 Feb;35(2):673-8.

3(0,0,0,3) Details
12660222 Maccarrone M, Battista N, Meloni M, Bari M, Galleri G, Pippia P, Cogoli A, Finazzi-Agro A: Creating conditions similar to those that occur during exposure of cells to microgravity induces apoptosis in human lymphocytes by 5-lipoxygenase-mediated mitochondrial uncoupling and cytochrome c release. J Leukoc Biol. 2003 Apr;73(4):472-81.


The intracellular calcium chelator EGTA-acetoxymethylester reduced 5-LOX activity and apoptosis to 30-40% of controls, whereas the p38 mitogen-activated protein kinase inhibitor SB203580 was ineffective.
1(0,0,0,1) Details