Protein Information

Name Myosin
Synonyms Myosin

Compound Information

Name oryzalin
CAS 4-(dipropylamino)-3,5-dinitrobenzenesulfonamide

Reference List

PubMed Abstract RScore(About this table)
10470016 Poulsen NC, Spector I, Spurck TP, Schultz TF, Wetherbee R: Diatom gliding is the result of an actin-myosin motility system. Cell Motil Cytoskeleton. 1999;44(1):23-33.

No effect on diatom gliding was observed using the cytochalasins, known actin inhibitors, or the microtubule-inhibitors oryzalin and nocodazole.
4(0,0,0,4) Details
20033230 Zheng M, Wang Q, Teng Y, Wang X, Wang F, Chen T, Samaj J, Lin J, Logan DC: The speed of mitochondrial movement is regulated by the cytoskeleton and myosin in Picea wilsonii pollen tubes. Planta. 2010 Mar;231(4):779-91. Epub 2009 Dec 24.

Oryzalin induced curved mitochondrial trajectories with similar velocities as in the control pollen tubes.
3(0,0,0,3) Details
9634216 Ehler LL, Dutcher SK: Pharmacological and genetic evidence for a role of rootlet and phycoplast microtubules in the positioning and assembly of cleavage furrows in Chlamydomonas reinhardtii. Cell Motil Cytoskeleton. 1998;40(2):193-207.


Actin and myosin were mislocalized to additional rootlet microtubules in the cyt2-1 strain, and this mislocalization was correlated with the presence of additional cleavage furrows.
1(0,0,0,1) Details
11886885 Van Gestel K, Kohler RH, Verbelen JP: Plant mitochondria move on F-actin, but their positioning in the cortical cytoplasm depends on both F-actin and microtubules. J Exp Bot. 2002 Apr;53(369):659-67.

It is inhibited by the actin filament disrupting drug latrunculin B, the myosin ATPase inhibitor 2,3-butanedione 2-monoxime and the sulphydryl-modifying agent N-ethylmaleimide.
The microtubule disrupting drug oryzalin did not affect the movement of mitochondria itself, but it slightly stimulated the recruitment of cytoplasmic strands, along which mitochondria travel.
1(0,0,0,1) Details
17245769 Lovy-Wheeler A, Cardenas L, Kunkel JG, Hepler PK: Differential organelle movement on the actin cytoskeleton in lily pollen tubes. Cell Motil Cytoskeleton. 2007 Mar;64(3):217-32.


These movements are dependent on the actin cytoskeleton, because they are strongly perturbed by the anti-microfilament drug, latrunculin-B, and unaffected by the anti-microtubule agent, oryzalin.
0(0,0,0,0) Details