| Name | demethylase |
|---|---|
| Synonyms | DMTase; Demethylase; MBD 2; MBD2; Methyl CpG binding domain protein 2; Methyl CpG binding protein MBD2; NY CO 41; Demethylases… |
| Name | dicamba |
|---|---|
| CAS | 3,6-dichloro-2-methoxybenzoic acid |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 15855162 | Herman PL, Behrens M, Chakraborty S, Chrastil BM, Barycki J, Weeks DP: A three-component dicamba O-demethylase from Pseudomonas maltophilia, strain DI-6: gene isolation, characterization, and heterologous expression. J Biol Chem. 2005 Jul 1;280(26):24759-67. Epub 2005 Apr 26. Mixtures of the three highly purified recombinant dicamba O-demethylase components overexpressed in Escherichia coli converted dicamba to DCSA with an efficiency similar to that of the native enzyme, suggesting that all of the components required for optimal enzymatic activity have been identified. |
136(1,2,6,6) | Details |
| 15820213 | Chakraborty S, Behrens M, Herman PL, Arendsen AF, Hagen WR, Carlson DL, Wang XZ, Weeks DP: A three-component dicamba O-demethylase from Pseudomonas maltophilia, strain DI-6: purification and characterization. Arch Biochem Biophys. 2005 May 1;437(1):20-8. Dicamba O-demethylase is a multicomponent enzyme that catalyzes the conversion of the herbicide 2-methoxy-3,6-dichlorobenzoic acid (dicamba) to 3,6-dichlorosalicylic acid (DCSA). |
68(0,2,3,3) | Details |
| 19616009 | D'Ordine RL, Rydel TJ, Storek MJ, Sturman EJ, Moshiri F, Bartlett RK, Brown GR, Eilers RJ, Dart C, Qi Y, Flasinski S, Franklin SJ: Dicamba monooxygenase: structural insights into a dynamic Rieske oxygenase that catalyzes an exocyclic monooxygenation. J Mol Biol. 2009 Sep 18;392(2):481-97. Epub 2009 Jul 15. Dicamba (2-methoxy-3,6-dichlorobenzoic acid) O-demethylase (DMO) is the terminal Rieske oxygenase of a three-component system that includes a ferredoxin and a reductase. |
6(0,0,1,1) | Details |
| 16535584 | Wang X, Li B, Herman PL, Weeks DP: A Three-Component Enzyme System Catalyzes the O Demethylation of the Herbicide Dicamba in Pseudomonas maltophilia DI-6. Appl Environ Microbiol. 1997 Apr;63(4):1623-1626. The activity of dicamba O-demethylase was dependent on and required and Mg (sup2+). |
6(0,0,1,1) | Details |
| 11344134 | Naidu D, Ragsdale SW: Characterization of a three-component O-demethylase from Moorella thermoacetica. J Bacteriol. 2001 Jun;183(11):3276-81. |
2(0,0,0,2) | Details |
| 1755024 | Moody DE, Narloch BA, Shull LR, Hammock BD: The effect of structurally divergent herbicides on mouse liver xenobiotic-metabolizing enzymes (P-450-dependent mono-oxygenases, epoxide hydrolases and glutathione S-transferases) and carnitine acetyltransferase. Toxicol Lett. 1991 Dec;59(1-3):175-85. Chlorfiurecol, trifluralin, alachlor, propham, MCPP and 2,4-DP caused increases in phase I (cytochrome P-450, ethoxycoumarin O-deethylase, and/or aminopyrine N-demethylase) and phase II (microsomal epoxide hydrolase and cytosolic glutathione S-transferase) activities. Dicamba, at the dose employed, caused mortality and decreases in some of the enzymes monitored. |
1(0,0,0,1) | Details |
| 19616011 | Dumitru R, Jiang WZ, Weeks DP, Wilson MA: Crystal structure of dicamba monooxygenase: a Rieske nonheme oxygenase that catalyzes oxidative demethylation. J Mol Biol. 2009 Sep 18;392(2):498-510. Epub 2009 Jul 15. This first crystal structure of a Rieske demethylase shows that the Rieske oxygenase structural scaffold can be co-opted to perform varied types of reactions on xenobiotic substrates. |
1(0,0,0,1) | Details |