Protein Information

Name IL 12 (protein family or complex)
Synonyms Cytotoxic lymphocyte maturation factor; Cytotoxic lymphocyte maturation factors; IL 12; IL12; Natural killer cell stimulatory factor; Natural killer cell stimulatory factors

Compound Information

Name MAA
CAS methylarsonic acid

Reference List

PubMed Abstract RScore(About this table)
17198085 Wesa A, Kalinski P, Kirkwood JM, Tatsumi T, Storkus WJ: Polarized type-1 dendritic cells (DC1) producing high levels of IL-12 family members rescue patient TH1-type antimelanoma CD4+ T cell responses in vitro. J Immunother. 2007 Jan;30(1):75-82.

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18550015 Duryee MJ, Klassen LW, Jones BL, Willis MS, Tuma DJ, Thiele GM: Increased immunogenicity to P815 cells modified with malondialdehyde and acetaldehyde. Int Immunopharmacol. 2008 Aug;8(8):1112-8. Epub 2008 Apr 28.


Studies to assess IL-12 stimulation showed that peritoneal macrophages from P815 and PBS immunized animals produced modest amounts of IL-12 (20 and 35 pg/ml) when stimulated with Alb or MAA-Alb.
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