Protein Information

Name NADPH cytochrome P450 reductase
Synonyms CPR; CYPOR; Cytochrome P 450 reductase; Cytochrome P450 reductase; NADPH cytochrome P450 reductase; NADPH cytochrome P450 reductase; P450 (cytochrome) oxidoreductase; P450R…

Compound Information

Name 2,4-D
CAS 2-(2,4-dichlorophenoxy)acetic acid

Reference List

PubMed Abstract RScore(About this table)
1852715 Santagostino A, Leone MP, Maci R, Casale A, Marabini L: Effects of phenoxyacetic acid herbicides on chicken embryo liver drug metabolizing enzymes. Pharmacol Toxicol. 1991 Feb;68(2):110-4.

The higher dose of MCPA increased NADPH-cytochrome P450 reductase. 2,4-D treatment increased by activity of glutathione-S-transferases in the hepatic post-microsomal fraction while MCPA increased them at the lower dose and significantly reduced them at the higher.
31(0,1,1,1) Details