Protein Information

Name CYP1
Synonyms 1 alpha hydroxylase; VDR; CYP 1; CYP1; 1 alpha hydroxylase deficiency; 25 hydroxyvitamin d3 1 alpha hydroxylase; 25 OHD 1 alpha hydroxylase; 25 hydroxycholecalciferol 1 hydroxylase deficiency…

Compound Information

Name 2,4-D
CAS 2-(2,4-dichlorophenoxy)acetic acid

Reference List

PubMed Abstract RScore(About this table)
10910964 Badawi AF, Cavalieri EL, Rogan EG: Effect of chlorinated hydrocarbons on expression of cytochrome P450 1A1, 1A2 and 1B1 and 2- and 4-hydroxylation of 17beta-estradiol in female Sprague-Dawley rats. Carcinogenesis. 2000 Aug;21(8):1593-9.

TCDD was the most potent inducer for CYP1 enzyme mRNA and for the 2- and 4-hydroxylation of E (2). 2,4-D and DED induced similar responses, but less than that of TCDD.
82(1,1,1,2) Details