Protein Information

Name albumin
Synonyms ALB; Albumin; PRO0883; PRO0903; PRO1341; PRO1708; PRO2044; PRO2619…

Compound Information

Name 2,4-D
CAS 2-(2,4-dichlorophenoxy)acetic acid

Reference List

PubMed Abstract RScore(About this table)
7963590 Skladal P, Minunni M, Mascini M, Kolar V, Franek M: Characterization of monoclonal antibodies to 2,4-dichlorophenoxyacetic acid using a piezoelectric quartz crystal microbalance in solution. J Immunol Methods. 1994 Nov 10;176(1):117-25.

The activated carboxylic group of 2,4-D was linked either directly to the silanized surface or through hexamethylenediamine or albumin as a macromolecule.
162(2,2,2,2) Details
11761670 Kossmann S, Tustanowski J, Kolodziej B: [Renal dysfunction in chemical plant workers producing dust pesticides] . Med Pr. 2001;52(4):253-6.

In order to assess the renal function in the workers, the concentrations of serum creatinine and uric acid, protein, albumin and alpha 1-microglobulin, as well as the activity of alkaline phosphatase (AP) and N-acetyl-beta-glucosaminidase (NAG) in urine were determined.
The active substances with concentrations ranging from 10 to 75% in the final product were as follows: triazines, dithiocarbamates, carbendazim and thiophanate-methyl, captan, phenylureas, cupric oxychloride and occasionally also carbamates, dodine and 2,4-D.
2(0,0,0,2) Details
8540221 Paulino CA, Palermo-Neto J: Effects of acute 2,4-dichlorophenoxyacetic acid on cattle serum components and enzyme activities. Vet Hum Toxicol. 1995 Aug;37(4):329-32.

The acute toxicity of 2,4-dichlorophenoxyacetic acid (2,4-D) was studied in cattle.
Serum aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (AP), O-glutamyl transferase (O-GT), creatine kinase (CK), lactate dehydrogenase (LDH) activities and urea, creatinine, glucose, total proteins and albumin levels were determined at intervals after dosing.
1(0,0,0,1) Details
762661 Pritchard JB, James MO: Determinants of the renal handling of 2, 4-dichlorophenoxyacetic acid by winter flounder. J Pharmacol Exp Ther. 1979 Feb;208(2):280-6.

Examination of the effects of added proteins on in vitro uptake showed that protein binding could limit 2,4-D transport but that flounder plasma (low in albumin) was far less effective than bovine serum albumin in binding and inhibition of transport.
81(1,1,1,1) Details
2904874 Elo HA, Hervonen H, Ylitalo P: Comparative study on cerebrovascular injuries by three chlorophenoxyacetic acids (2,4-D, 2,4,5-T and MCPA). Comp Biochem Physiol C. 1988;90(1):65-8.

At toxic doses in rats, 2,4-dichlorophenoxyacetic acid (2,4-D) and 2-methyl-4-chlorophenoxyacetic acid (MCPA) caused injuries in blood vessels in the brain. 2. 2,4-D caused extravasations of the circulating Evans blue-albumin complex also in the spinal cord. 3.
31(0,1,1,1) Details
1726651 Paulino CA, Palermo-Neto J: Effects of acute 2,4-dichlorophenoxyacetic acid intoxication on some rat serum components and enzyme activities. Braz J Med Biol Res. 1991;24(2):195-8.

The present study was undertaken to investigate the effects of acute 2,4-dichlorophenoxyacetic acid (2,4-D) intoxication (0.6 g/kg, po) on lactate dehydrogenase, alkaline phosphatase, aspartate aminotransferase, alanine aminotransferase, amylase, creatinine, glucose, total protein and albumin levels in rats.
6(0,0,1,1) Details
7229910 Fang SC, Lindstrom FT: In vitro binding of 14C-labeled acidic compounds to serum albumin and their tissue distribution in the rat. J Pharmacokinet Biopharm. 1980 Dec;8(6):583-97.

Among phenoxyacetic acids, the binding affinity to BSA was highest for 2,4,5-trichlorophenoxyacetic acid (2,4,5-T), which was approximately 4-, 24-, and 160-fold greater than those for 2,4-dichlorophenoxyacetic acid (2,4-D), o-chlorophenoxyacetic acid (CPA), and phenoxyacetic acid (PAA), respectively.
There were two bound to serum albumins of other mammalian species.
2(0,0,0,2) Details
8888538 Paulino CA, Guerra JL, Oliveira GH, Palermo-Neto J: Acute, subchronic and chronic 2,4-dichlorophenoxyacetic acid (2,4-D) intoxication in rats. Vet Hum Toxicol. 1996 Oct;38(5):348-52.

0(0,0,0,0) Details