| Name | angiotensin II |
|---|---|
| Synonyms | AGT; ANG II; ANHU; Angiotensin I; Angiotensin II; Angiotensinogen; Angiotensinogen precursor; SERPINA 8… |
| Name | SMA |
|---|---|
| CAS | sodium 2-chloroacetate |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19012043 | Kim MY, Baik SK, Park DH, Jang YO, Suk KT, Yea CJ, Lee IY, Kim JW, Kim HS, Kwon SO, Cho MY, Ko SB, Chang SJ, Um SH, Han KH: Angiotensin receptor blockers are superior to angiotensin-converting enzyme inhibitors in the suppression of hepatic fibrosis in a bile duct-ligated rat model. J Gastroenterol. 2008;43(11):889-96. Epub 2008 Nov 18. BACKGROUND: Angiotensin blockade such as with an angiotensin II receptor blocker (ARB) or angiotensinconverting enzyme inhibitor (ACEI) has antifibrotic properties. |
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| 18949565 | Tuncdemir M, Ozturk M: The effects of ACE inhibitor and angiotensin receptor blocker on clusterin and apoptosis in the kidney tissue of streptozotocin-diabetic rats. J Mol Histol. 2008 Dec;39(6):605-16. Epub 2008 Oct 24. We also aimed to investigate the post-effects of angiotensin II blockage treatment on clusterin expression and to compare these with apoptosis. |
1(0,0,0,1) | Details |
| 17651610 | Long X, Xiong SD, Xiong WN, Xu YJ, Zhang ZX, Cao Y, Chen J, Xu XH: [Losartan inhibited angiotensin induced human lung fibroblast transformation and collagen synthesis]. Zhonghua Jie He He Hu Xi Za Zhi. 2007 Apr;30(4):273-8. OBJECTIVE: To observe the induction of cell transdifferentiation, connective tissue growth factor (CTGF) expression and collagen production of human lung fibroblast (HLF) by angiotensin II (Ang II), and to investigate the inhibitory effect of Ang II receptor antagonist-losartan on this process. |
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| 18633183 | Roson MI, Cao G, Della Penna S, Gorzalczany S, Pandolfo M, Toblli JE, Fernandez BE: Angiotensin II increases intrarenal transforming growth factor-beta1 in rats submitted to sodium overload independently of blood pressure. Hypertens Res. 2008 Apr;31(4):707-15. |
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| 18571460 | Kim YM, Jeon ES, Kim MR, Jho SK, Ryu SW, Kim JH: Angiotensin II-induced differentiation of adipose tissue-derived mesenchymal stem cells to smooth muscle-like cells. Int J Biochem Cell Biol. 2008;40(11):2482-91. Epub 2008 May 18. |
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| 19470381 | Wu M, Han M, Li J, Xu X, Li T, Que L, Ha T, Li C, Chen Q, Li Y: 17beta- inhibits angiotensin II-induced cardiac myofibroblast differentiation. Eur J Pharmacol. 2009 Aug 15;616(1-3):155-9. Epub 2009 May 24. |
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| 20232302 | Roson MI, Della Penna SL, Cao G, Gorzalczany S, Pandolfo M, Toblli JE, Fernandez BE: Different protective actions of losartan and tempol on the renal inflammatory response to acute sodium overload. J Cell Physiol. 2010 Mar 15. The aim of this work was to study the role of local intrarenal angiotensin II (Ang II) and the oxidative stress in the up-regulation of pro-inflammatory cytokines expression observed in rats submitted to an acute sodium overload. |
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| 17666953 | Li T, Liu L, Liu J, Ming J, Xu J, Yang G, Zhang Y: Mechanisms of Rho kinase regulation of vascular reactivity following hemorrhagic shock in rats. Shock. 2008 Jan;29(1):65-70. Angiotensin II (Ang-II), the Rho kinase stimulator, significantly improved hypoxia or hemorrhagic shock-induced decrease of vascular reactivity and sensitivity. |
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| 20353822 | Lang YD, Hung CL, Wu TY, Wang LF, Chen CM: The renin-angiotensin system mediates hyperoxia-induced collagen production in human lung fibroblasts. Free Radic Biol Med. 2010 Mar 27. Angiotensin (Ang) II induces human lung fibroblast proliferation and stimulates collagen synthesis. |
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| 19229613 | Xiao F, Yu K, Dong F, Liang Y, Jun C, Wei H: The GABAB receptor inhibits activation of hepatic stellate cells. Dig Dis Sci. 2010 Feb;55(2):261-7. Epub 2009 Feb 20. BACKGROUND/AIMS: Angiotensin II (Ang II) plays an important role in the activation of hepatic stellate cells (HSCs). |
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| 19523990 | Yang JH, Cai Y, Duan XH, Ma CG, Wang X, Tang CS, Qi YF: Intermedin 1-53 inhibits rat cardiac fibroblast activation induced by angiotensin II. Regul Pept. 2009 Nov 27;158(1-3):19-25. Epub 2009 Jun 11. |
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| 19781194 | Jiang T, Zhou QS, Pi L, Huang B: [Role of angiotensin II and JAK2 signal pathway in transdifferentation of renal tubular cells in mice after acute ischemic followed by reperfusion]. Zhonghua Bing Li Xue Za Zhi. 2009 Jul;38(7):466-71. |
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| 19721329 | Fan YY, Nishiyama A, Fujisawa Y, Kobori H, Nakano D, Matsuura J, Hase N, Hitomi H, Kiyomoto H, Urata H, Kohno M: Contribution of chymase-dependent angiotensin II formation to the progression of tubulointerstitial fibrosis in obstructed kidneys in hamsters. J Pharmacol Sci. 2009 Sep;111(1):82-90. Epub 2009 Aug 29. |
2(0,0,0,2) | Details |
| 17884089 | Wakisaka O, Takahashi N, Shinohara T, Ooie T, Nakagawa M, Yonemochi H, Hara M, Shimada T, Saikawa T, Yoshimatsu H: Hyperthermia treatment prevents angiotensin II-mediated atrial fibrosis and fibrillation via induction of heat-shock protein 72. J Mol Cell Cardiol. 2007 Nov;43(5):616-26. Epub 2007 Aug 16. |
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| 19403408 | Ying SS, Li X, Huang ML, Meng Y, Zhang ZS: [Effect of angiotensin1-7 on alpha-smooth muscle actin protein expression in rat hepatic stellate cells]. Nan Fang Yi Ke Da Xue Xue Bao. 2009 Apr;29(4):732-3. OBJECTIVE: To investigate the effect of angiotensin II and angiotensin1-7 on alpha-smooth muscle actin (alpha-SMA)-induced Ca (2+)-independent pathways mediated by Rho kinase2 in hepatic stellate cells (HSCs). |
1(0,0,0,1) | Details |
| 19616542 | Del Prete D, Ceol M, Anglani F, Vianello D, Tiralongo E, Valente M, Graziotto R, Bonfante L, Scaparrotta G, Furian L, Rigotti P, Gambaro G, D'Angelo A: Early activation of fibrogenesis in transplanted kidneys: a study on serial renal biopsies. Exp Mol Pathol. 2009 Oct;87(2):141-5. Epub 2009 Jul 16. Morphometric alpha SMA and TGF beta 1 analysis, and Masson's Trichrome staining were performed. mRNA levels of angiotensinogen, renin, ACE, AT1-R, AT2-R, TGF beta 1, BMP-7, Coll III, fibronectin and alpha SMA were analyzed by real-time RT/PCR. |
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| 19650157 | Osterreicher CH, Taura K, De Minicis S, Seki E, Penz-Osterreicher M, Kodama Y, Kluwe J, Schuster M, Oudit GY, Penninger JM, Brenner DA: Angiotensin-converting-enzyme 2 inhibits liver fibrosis in mice. Hepatology. 2009 Sep;50(3):929-38. HSCs express the Ang (1-7) receptor Mas and Ang (1-7) inhibited Ang II-induced phosphorylation of extracellular signal-regulated kinase (ERK)-1/2 in cultured HSCs. |
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| 20348013 | Saad S, Stanners SR, Yong R, Tang O, Pollock CA: NOTCH MEDIATED EPITHELIAL TO MESENCHYMAL TRANSFORMATION IS ASSOCIATED WITH INCREASED EXPRESSION OF THE SNAIL TRANSCRIPTION FACTOR. Int J Biochem Cell Biol. 2010 Mar 25. EMT was induced by exposure to transforming growth factor beta-1 (TGFbeta1) and angiotensin II (AngII). |
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| 18976289 | Djamali A, Vidyasagar A, Adulla M, Hullett D, Reese S: Nox-2 is a modulator of fibrogenesis in kidney allografts. Am J Transplant. 2009 Jan;9(1):74-82. Epub 2008 Oct 31. Cyclosporine A, TGF-beta1 and angiotensin II increased Nox-2 mRNA levels 2- to 7-fold in vitro (NRK52E cells). |
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| 19579288 | Bruno S, Bussolati B, Grange C, Collino F, di Cantogno LV, Herrera MB, Biancone L, Tetta C, Segoloni G, Camussi G: Isolation and characterization of resident mesenchymal stem cells in human glomeruli. Stem Cells Dev. 2009 Jul-Aug;18(6):867-80. Moreover, Gl-MSC when cultured in appropriate conditions, acquired mesangial cell markers such as alpha-smooth muscle actin (alpha-SMA) and angiotensin II (AT-II) receptor I. |
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| 19371232 | Lubel JS, Herath CB, Tchongue J, Grace J, Jia Z, Spencer K, Casley D, Crowley P, Sievert W, Burrell LM, Angus PW: Angiotensin-(1-7), an alternative metabolite of the renin-angiotensin system, is up-regulated in human liver disease and has antifibrotic activity in the bile-duct-ligated rat. Clin Sci. 2009 Sep 14;117(11):375-86. Ang-(1-7) (angiotensin-1-7), a peptide product of the recently described ACE (angiotensin-converting enzyme) homologue ACE2, opposes the harmful actions of AngII (angiotensin II) in cardiovascular tissues, but its role in liver disease is unknown. |
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| 19223006 | Nishikimi T, Inaba-Iemura C, Ishimura K, Tadokoro K, Koshikawa S, Ishikawa K, Akimoto K, Hattori Y, Kasai K, Minamino N, Maeda N, Matsuoka H: Natriuretic peptide/natriuretic peptide receptor-A (NPR-A) system has inhibitory effects in renal fibrosis in mice. Regul Pept. 2009 Apr 10;154(1-3):44-53. Epub 2009 Feb 15. In contrast, ANP pre-treatment significantly improved morphological changes with increase of tissue levels and reduction in the mRNA expression level of TGF-beta, collagen I, collagen III, PAI-1, ICAM-1, osteopontin, MCP-1, renin, and angiotensinogen. |
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