| Name | myosin phosphatase target subunit 1 |
|---|---|
| Synonyms | MBS; MYPT 1; MYPT1; Myosin phosphatase target subunit 1; Myosin phosphatase targeting subunit 1; PPP1R12A; Protein phosphatase 1 regulatory subunit 12A; Protein phosphatase myosin binding subunit… |
| Name | SMA |
|---|---|
| CAS | sodium 2-chloroacetate |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 20006464 | Wu G, Tu Y, Jia R: The influence of fasudil on the epithelial-mesenchymal transdifferentiation of renal tubular epithelial cells from diabetic rats. Biomed Pharmacother. 2010 Feb;64(2):124-9. Epub 2009 Oct 23. Changes in the MYPT1 phosphorylation profile and alpha-SMA, E-cadherin and membrane beta-catenin expression were revealed by western blot. |
3(0,0,0,3) | Details |
| 18929559 | Diah S, Zhang GX, Nagai Y, Zhang W, Gang L, Kimura S, Hamid MR, Tamiya T, Nishiyama A, Hitomi H: induces myofibroblastic transdifferentiation and collagen gene expression through the Rho-kinase dependent signaling pathway in rat mesangial cells. Exp Cell Res. 2008 Dec 10;314(20):3654-62. Epub 2008 Oct 7. Stimulation with (1 nmol/L) significantly increased phosphorylation of myosin phosphatase target subunit-1 (MYPT-1), a marker of Rho-kinase activity, with a peak at 20 min in RMCs. |
2(0,0,0,2) | Details |
| 19298234 | Freitas MR, Eto M, Kirkbride JA, Schott C, Sassard J, Stoclet JC: Y27632, a Rho-activated kinase inhibitor, normalizes dysregulation in alpha1-adrenergic receptor-induced contraction of Lyon hypertensive rat artery smooth muscle. Fundam Clin Pharmacol. 2009 Apr;23(2):169-78. Epub 2009 Mar 9. In response to PE stimulation, phosphorylation of CPI-17, a phosphorylation-dependent myosin phosphatase inhibitor protein, and MYPT1 at Thr853, the inhibitory phosphorylation site of the myosin phosphatase regulatory subunit, was increased in LN SMA, but remained unchanged in LH SMA. |
1(0,0,0,1) | Details |