Protein Information

Name myoglobin
Synonyms MB; Myoglobin; PVALB; Myoglobins

Compound Information

Name ferrous sulfate
CAS sulfuric acid iron(2+) salt (1:1)

Reference List

PubMed Abstract RScore(About this table)
6827383 Park YW, Mahoney AW, Cornforth DP, Collinge SK, Hendricks DG: Bioavailability to anemic rats of iron from fresh, cooked or nitrosylated hemoglobin and myoglobin. J Nutr. 1983 Mar;113(3):680-7.

In experiment 1, the bioavailabilities of porcine and bovine hemoglobins were about one-third that for ferrous sulfate regardless of hemoglobin treatments.
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6625830 Stekel A, Amar M, Calvo E, Chadud P, Hertrampf E, Llaguno S, Olivares M, Pizarro F: Nutritional significance of interactions between iron and food components. Arch Latinoam Nutr. 1983 Mar;33(1):33-41.


Heme iron present in hemoglobin and myoglobin, is well absorbed and is relatively unaffected by diet composition.
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12049792 Horejsi R, Jung C, Moller R, Tafeit E, Reibnegger G: Generation of carbon monoxide and iron from hemeproteins in the presence of 7,8-dihydroneopterin. Biochim Biophys Acta. 2002 Jun 6;1571(2):124-30.


Effects of 7,8-dihydroneopterin were investigated on (met) myoglobin and (met) hemoglobin.
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1654842 Kanner J, Harel S, Granit R: Nitric oxide as an antioxidant. Arch Biochem Biophys. 1991 Aug 15;289(1):130-6.


Myoglobin in several forms such as metmyoglobin, oxymyoglobin, and nitric oxide-myoglobin were interacted with an equimolar concentration of hydrogen peroxide.
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12840181 Pizarro F, Olivares M, Hertrampf E, Mazariegos DI, Arredondo M: Heme-iron absorption is saturable by heme-iron dose in women. J Nutr. 2003 Jul;133(7):2214-7.

In developed countries where meat is an important constituent of the diet, much of the dietary iron is in the heme-iron form as hemoglobin and myoglobin.
Through the use of iron isotopes ((59) Fe and (55) Fe), the studies were performed to characterize the dose-response curve of non-heme-iron absorption (ferrous sulfate), and to establish the dose-response curve of heme-iron absorption (hemoglobin).
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