Protein Information

Name NK1
Synonyms BY55; CD160; CD160 antigen; CD160 antigen precursor; CD160 molecule; NK1; NK28; Natural killer cell receptor BY55…

Compound Information

Name diquat
CAS

Reference List

PubMed Abstract RScore(About this table)
11323143 Anton PM, Theodorou V, Fioramonti J, Bueno L: Chronic low-level administration of diquat increases the nociceptive response to gastric distension in rats: role of mast cells and tachykinin receptor activation. Pain. 2001 May;92(1-2):219-27.

Both NK1 and NK2 receptor antagonists blocked the enhanced CVD response induced by diquat and prevented mast cell degranulation.
82(1,1,1,2) Details
15046732 Larauche M, Anton PM, Peiro G, Eutamene H, Bueno L, Fioramonti J: Role of capsaicin-sensitive afferent nerves in different models of gastric inflammation in rats. Auton Neurosci. 2004 Feb 27;110(2):89-97.

Gastritis was induced by mild (iodoacetamide, diquat, surgical duodeno-gastric reflux [DGR]) and strong (70% ethanol, indomethacin) inflammatory agents.
Antagonists of the CGRP1 and NK1 receptors, hCGRP8-37 and SR140333, were administered in rats treated with iodoacetamide and ethanol.
1(0,0,0,1) Details