| 7097779 |
Rao M, Eichberg MR, Oro J: Synthesis of phosphatidylcholine under possible primitive earth conditions. J Mol Evol. 1982;18(3):196-202.
Using a primitive Earth evaporating pond model, the synthesis of phosphatidylcholine was accomplished when a reaction mixture of choline chloride and disodium phosphatidate, in the presence of cyanamide and traces of acid, was evaporated and heated at temperatures ranging from 25 degrees to 100 degrees C for 7 hours.
On enzymatic hydrolysis with phospholipase A2 and phospholipase C, lysophosphatidylcholine and phosphorylcholine were formed, respectively. |
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