| Name | PLA2 |
|---|---|
| Synonyms | 85 kDa calcium independent phospholipase A2; PLA 2; PLA2; CaI PLA2; GVI; GVI PLA2; Group VI phospholipase A2; INAD 1… |
| Name | lindane |
|---|---|
| CAS | (1α,2α,3β,4α,5α,6β)-1,2,3,4,5,6-hexachlorocyclohexane |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 10653519 | Tithof PK, Olivero J, Ruehle K, Ganey PE: Activation of neutrophil -dependent and -independent phospholipases A2 by organochlorine compounds. Toxicol Sci. 2000 Jan;53(1):40-7. Therefore, studies were performed to determine if the organochlorine pesticides, lindane and dieldrin, activate neutrophils to produce O2- by a mechanism that requires PLA2. |
245(3,3,3,5) | Details |
| 16686424 | Mariussen E, Fonnum F: Neurochemical targets and behavioral effects of organohalogen compounds: an update. Crit Rev Toxicol. 2006 Mar;36(3):253-89. For instance, several reports have shown that OHCs alter neurotransmitter functions in CNS and Ca2+ homeostatic processes, induce protein kinase C (PKC) and phospholipase A2 (PLA2) mobilization, and induce oxidative stress. In the 1970s it was discovered that PCBs and some chlorinated pesticides, such as lindane, have potentials after both acute and chronic exposure. |
1(0,0,0,1) | Details |