| Name | metallothionein (protein family or complex) |
|---|---|
| Synonyms | Metallothionein; Metallothioneins |
| Name | acrolein |
|---|---|
| CAS | 2-propenal |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 18921984 | Thompson CA, Burcham PC: Genome-Wide Transcriptional Responses to Acrolein. . Chem Res Toxicol. 2008 Oct 16. Transcript levels of several members of the metallothionein class of cytoprotective metal-chelating proteins decreased strongly in response to acrolein. |
6(0,0,1,1) | Details |
| 19548348 | Thompson CA, Burcham PC: Genome-wide transcriptional responses to acrolein. . Chem Res Toxicol. 2008 Dec;21(12):2245-56. Transcript levels of several members of the metallothionein class of cytoprotective metal-chelating proteins decreased strongly in response to acrolein. |
6(0,0,1,1) | Details |
| 19838947 | Lee HS, Lee SY, Ha HL, Han DC, Han JM, Jeong TS, Yu DY, Yeom YI, Kwon BM, Moon EY: 2'-Benzoyloxycinnamaldehyde inhibits tumor growth in H-ras12V transgenic mice via downregulation of metallothionein. Nutr Cancer. 2009;61(5):723-34. |
4(0,0,0,4) | Details |
| 20091025 | Mizukami S, Ichimura R, Kemmochi S, Taniai E, Shimamoto K, Ohishi T, Takahashi M, Mitsumori K, Shibutani M: Induction of GST-P-positive proliferative lesions facilitating lipid peroxidation with possible involvement of transferrin receptor up-regulation and ceruloplasmin down-regulation from the early stage of liver tumor promotion in rats. Arch Toxicol. 2010 Apr;84(4):319-31. Epub 2009 Dec 20. To elucidate the role of metal-related molecules in hepatocarcinogenesis, we examined immunolocalization of transferrin receptor (Tfrc), ceruloplasmin (Cp) and metallothionein (MT)-1/2 in relation to liver cell foci positive for glutathione-S-transferase placental form (GST-P) in the early stage of tumor promotion by fenbendazole (FB), phenobarbital, piperonyl butoxide or thioacetamide in a rat two-stage hepatocarcinogenesis model. To estimate the involvement of oxidative stress responses to the promotion, immunolocalization of malondialdehyde and acrolein was similarly examined. |
1(0,0,0,1) | Details |
| 16930132 | Hao Q, Maret W: Aldehydes release zinc from proteins. FEBS J. 2006 Sep;273(18):4300-10. Epub 2006 Aug 23. Thus both and acrolein induce the expression of metallothionein and modulate protein tyrosine phosphatase activity in a zinc-dependent way. |
37(0,1,2,2) | Details |