| Name | IL 1beta |
|---|---|
| Synonyms | Catabolin; IL 1; IL 1 beta; IL 1B; IL1 beta; IL1B; IL1F2; Interleukin 1… |
| Name | acrolein |
|---|---|
| CAS | 2-propenal |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 11956484 | Ribeiro RA, Freitas HC, Campos MC, Santos CC, Figueiredo FC, Brito GA, Cunha FQ: Tumor necrosis factor-alpha and interleukin-1beta mediate the production of involved in the pathogenesis of ifosfamide induced hemorrhagic cystitis in mice. J Urol. 2002 May;167(5):2229-34. Ifosfamide injected mice were pretreated with 10 to 40 mg./kg. of the synthesis inhibitor L-NG-nitroarginine methyl ester, 80 mg./kg. of mesna, a chemical antagonist of acrolein and the urotoxic metabolite of ifosfamide, 50 microl. antiserum against TNF-alpha and IL-1beta per mouse, 45 mg./kg. of the selective TNF-alpha synthesis inhibitor thalidomide or 200 mg./kg. of the TNF-alpha and IL-1beta synthesis inhibitor pentoxifylline. |
85(1,1,1,5) | Details |
| 9266806 | Li L, Hamilton RF Jr, Taylor DE, Holian A: Acrolein-induced cell death in human alveolar macrophages. . Toxicol Appl Pharmacol. 1997 Aug;145(2):331-9. Acrolein caused a dose-dependent inhibition of release of IL-1beta, TNF-alpha, and IL-12. |
81(1,1,1,1) | Details |
| 17882968 | Ma YY, Shang MY, Li CH, Huo HR, Cai SQ, Jiang TL: [Structure-activity relationship of phenylallyl compounds inhibiting release in mouse cerebral microvascular endothelial cells induced by IL-1beta]. Yao Xue Xue Bao. 2007 Jul;42(7):798-802. |
5(0,0,0,5) | Details |
| 17048610 | Guo JY, Yang YX, Zhao BS, Liu HB, Li LF, Ma YY, Guo SY, Huo HR, Jiang TL: [Effect of 2-methoxycinnamaldehyde on activity of COX and release in cerebral microvascular endothelial cells stimulated by IL-1]. Zhongguo Zhong Yao Za Zhi. 2006 Jul;31(13):1087-90. |
4(0,0,0,4) | Details |
| 18310904 | Ma YY, Huo HR, Li CH, Zhao BS, Li LF, Sui F, Guo SY, Jiang TL: Effects of on release and TRPV4 expression in mouse cerebral microvascular endothelial cells induced by interleukin-1beta. Biol Pharm Bull. 2008 Mar;31(3):426-30. |
4(0,0,0,4) | Details |
| 17077517 | Guo JY, Huo HR, Yang YX, Li CH, Liu HB, Zhao BS, Li LF, Ma YY, Guo SY, Jiang TL: 2-methoxycinnamaldehyde reduces IL-1beta-induced prostaglandin production in rat cerebral endothelial cells. Biol Pharm Bull. 2006 Nov;29(11):2214-21. |
2(0,0,0,2) | Details |
| 16624280 | Guo JY, Huo HR, Zhao BS, Liu HB, Li LF, Ma YY, Guo SY, Jiang TL: reduces IL-1beta-induced cyclooxygenase-2 activity in rat cerebral microvascular endothelial cells. Eur J Pharmacol. 2006 May 10;537(1-3):174-80. Epub 2006 Mar 10. |
2(0,0,0,2) | Details |
| 11948286 | Malley SE, Vizzard MA: Changes in urinary bladder cytokine mRNA and protein after cyclophosphamide-induced cystitis. Physiol Genomics. 2002;9(1):5-13. Acute cystitis demonstrated the most robust changes (P IL-1beta, 330-fold increase; IL-2, 20-fold increase; IL-4, 8-fold increase; IL-6, 80-fold increase) in cytokine mRNA expression and TNF-alpha or TNF-beta mRNA were only increased (2-10-fold) after acute cystitis. |
1(0,0,0,1) | Details |
| 11566557 | Tuschl H, Kovac R: Langerhans cells and immature dendritic cells as model systems for screening of skin sensitizers. Toxicol In Vitro. 2001 Aug-Oct;15(4-5):327-31. Both the expression of surface markers and the induction of intracellular interleukin-1 beta (IL-1 beta) were analyzed. |
1(0,0,0,1) | Details |
| 17868967 | Chao LK, Hua KF, Hsu HY, Cheng SS, Lin IF, Chen CJ, Chen ST, Chang ST: inhibits pro-inflammatory cytokines secretion from monocytes/macrophages through suppression of intracellular signaling. Food Chem Toxicol. 2008 Jan;46(1):220-31. Epub 2007 Aug 8. Although has been reported to have contact sensitizing properties at high concentration (mM), we found that low concentration of (muM) inhibited the secretion of interleukin-1beta and tumor necrosis factor alpha within lipopolysaccharide (LPS) or lipoteichoic acid (LTA) stimulated murine J774A.1 macrophages. |
1(0,0,0,1) | Details |
| 19464576 | Liu DS, Liu WJ, Chen L, Ou XM, Wang T, Feng YL, Zhang SF, Xu D, Chen YJ, Wen FQ: a peroxisome proliferator-activated receptor-gamma agonist, attenuates acrolein-induced airway mucus hypersecretion in rats. Toxicology. 2009 Jun 16;260(1-3):112-9. Epub 2009 Apr 5. The expressions of Muc5ac protein and mRNA, and infiltration of inflammatory cells and levels of inflammatory cytokines (interleukin (IL)-1beta, IL-8 and tumor necrosis factor (TNF)-alpha) in bronchoalveolar lavage fluid (BALF) were detected with real-time PCR, Western blot, cell counting and ELISA. |
1(0,0,0,1) | Details |
| 19524605 | Python F, Goebel C, Aeby P: Comparative DNA microarray analysis of human monocyte derived dendritic cells and MUTZ-3 cells exposed to the moderate skin sensitizer Toxicol Appl Pharmacol. 2009 Sep 15;239(3):273-83. Epub 2009 Jun 12. Several studies have recently demonstrated that sensitizers induce a relevant up-regulation of activation markers such as CD86, CD54, IL-8 or IL-1beta in human myeloid cell lines (e.g., U937, MUTZ-3, THP-1) or in human peripheral blood monocyte-derived dendritic cells (PBMDCs). |
1(0,0,0,1) | Details |