| Name | GABA transaminase |
|---|---|
| Synonyms | (S) 3 amino 2 methylpropionate transaminase; 4 aminobutyrate aminotransferase; ABAT; ABAT protein; GABA aminotransferase; GABA transaminase; GABA AT; GABA T… |
| Name | chloralose |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 15619231 | Chen Z, Silva AC, Yang J, Shen J: Elevated endogenous level correlates with decreased fMRI signals in the rat brain during acute inhibition of GABA transaminase. J Neurosci Res. 2005 Feb 1;79(3):383-91. The time course of concentration after acute GABA transaminase inhibition was measured quantitatively in the alpha-chloralose-anesthetized rat brain using in vivo selective homonuclear polarization transfer spectroscopy. |
83(1,1,1,3) | Details |
| 8897466 | Manor D, Rothman DL, Mason GF, Hyder F, Petroff OA, Behar KL: The rate of turnover of cortical from [1-13C] is reduced in rats treated with the GABA-transaminase inhibitor vigabatrin (gamma-vinyl GABA). Neurochem Res. 1996 Sep;21(9):1031-41. Rates of turnover of cortical and from intravenously administered [1-13C] were measured in alpha-chloralose anesthetized rats 24 hours after receiving vigabatrin (500 mg/kg, i.p.) and in non-treated controls. |
3(0,0,0,3) | Details |
| 16797191 | Yang J, Shen J: Increased oxygen consumption in the somatosensory cortex of alpha-chloralose anesthetized rats during forepaw stimulation determined using MRS at 11.7 Tesla. Neuroimage. 2006 Sep;32(3):1317-25. Epub 2006 Jun 21. With markedly improved (1) H{(13) C} magnetic resonance spectroscopy technique and the use of high magnetic field strength of 11.7 T accessible to the current study, [4-(13) C] at 2.35 ppm was spectrally resolved from overlapping resonances of [4-(13) C] at 2.46 ppm and [2-(13) C] GABA at 2.28 ppm as well as the more distal [3-(13) C] and [3-(13) C] |
1(0,0,0,1) | Details |
| 11578600 | Mason GF, Martin DL, Martin SB, Manor D, Sibson NR, Patel A, Rothman DL, Behar KL: Decrease in synthesis rate in rat cortex following GABA-transaminase inhibition correlates with the decrease in GAD (67) protein. Brain Res. 2001 Sep 28;914(1-2):81-91. In the present study we compared V (GAD) in cortex of control and vigabatrin-treated rats under alpha-chloralose/70% nitrous oxide anesthesia, with total GAD activity and GAD isoform composition (GAD (65) and GAD (67)) measured by enzymatic assay and quantitative immunoblotting. |
1(0,0,0,1) | Details |
| 11827726 | Vidrio H, Medina M, Fernandez G, Lorenzana-Jimenez M, Campos AE: Enhancement of hydralazine hypotension by low doses of isoniazid. Gen Pharmacol. 2000 Oct;35(4):195-204. The influence of pretreatment with 1 through 300 mg/kg ip of isoniazid (ISO) on blood pressure and heart rate responses to 0.1 mg/kg iv of hydralazine (HYD) was assessed in rats anesthetized with chloralose--urethane. Similarly, ISO decreased cerebral (GABA) at the two highest doses; 30 mg/kg was without effect. |
1(0,0,0,1) | Details |
| 18554298 | Zhong MK, Shi Z, Zhou LM, Gao J, Liao ZH, Wang W, Gao XY, Zhu GQ: Regulation of cardiac sympathetic afferent reflex by (A) and GABA (B) receptors in paraventricular nucleus in rats. Eur J Neurosci. 2008 Jun;27(12):3226-32. Epub 2008 Jun 1. Under urethane (800 mg/kg) and alpha-chloralose (40 mg/kg) anesthesia, renal sympathetic nerve activity (RSNA), mean arterial pressure (MAP) and heart rate (HR) were recorded in sinoaortic-denervated and cervical-vagotomized rats. Vigabatrin (10 nmol), a selective GABA-transaminase inhibitor which increases endogenous level, abolished CSAR, and decreased baseline RSNA, MAP and HR. |
1(0,0,0,1) | Details |