Protein Information

Name gp91phox
Synonyms CGD; CGD91 PHOX; CYBB; Cytochrome B 245 heavy chain; Cytochrome B(558) beta chain; Cytochrome b(558) subunit beta; Cytochrome b 245 beta polypeptide; Cytochrome b558 subunit beta…

Compound Information

Name carbon tetrachloride
CAS tetrachloromethane

Reference List

PubMed Abstract RScore(About this table)
17105591 Novitskiy G, Potter JJ, Wang L, Mezey E: Influences of reactive oxygen species and nitric oxide on hepatic fibrogenesis. Liver Int. 2006 Dec;26(10):1248-57.

METHODS: Hepatic fibrosis was produced by carbon tetrachloride administered for 12 weeks in wild-type (WT) mice and in mice with knockout of either the gp91phox subunit of the NAD (P) H complex (gp91phox-/-) or of iNOS (iNOS (-/-)).
87(1,1,2,2) Details
19072832 Aram G, Potter JJ, Liu X, Wang L, Torbenson MS, Mezey E: Deficiency of nicotinamide adenine dinucleotide phosphate, reduced form oxidase enhances hepatocellular injury but attenuates fibrosis after chronic carbon tetrachloride administration. Hepatology. 2009 Mar;49(3):911-9.

Wild-type (WT) mice or mice with deficiency of the gp91 (phox) subunit of NADPH complex (gp91 (phox (-/-) )) were subjected to biweekly CCl (4) injections over 8 weeks, whereas controls were given isovolumetric injections of olive oil.
5(0,0,0,5) Details