| Name | SN2 |
|---|---|
| Synonyms | Amino acid transport system N2; JM24; SLC38A5; SLC38A5 protein; SN2; pp7194; SLC38A5 proteins; pp7194s |
| Name | ethylene dibromide |
|---|---|
| CAS | 1,2-dibromoethane |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 2128814 | Harris TM: NMR-studies of carcinogen reactions with DNA: ethylene dibromide and J Pharm Biomed Anal. 1990;8(2):195-204. Through the use of stereospecifically 1,2-dideuteriated ethylene dibromide, the mechanism of reaction has been shown to involve an odd number, i.e. three, of SN2 inversions. |
81(1,1,1,1) | Details |
| 2405457 | Pignatello JJ, Cohen SZ: Environmental chemistry of ethylene dibromide in soil and ground water. Rev Environ Contam Toxicol. 1990;112:1-47. Both SN1 and SN2 mechanisms have been proposed. |
1(0,0,0,1) | Details |
| 2134669 | Guengerich FP, Humphreys WG, Kim DH, Oida T, Cmarik JL: DNA- adducts derived from vic-dihaloalkanes: mechanisms of mutagenesis. Princess Takamatsu Symp. 1990;21:101-7. The conjugation of the prototype dihaloalkane ethylene dibromide (EDB) with (GSH) yields S-(2-bromoethyl) GSH, which gives rise to S-[2-(N7-guanyl) ethyl] GSH as the major DNA adduct (greater than or equal to 95%). All reaction steps have SN2 character. |
1(0,0,0,1) | Details |