| Name | cytochrome P450 (protein family or complex) |
|---|---|
| Synonyms | cytochrome P450; cytochrome P 450; CYP450; CYP 450 |
| Name | ethylene oxide |
|---|---|
| CAS | oxirane |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 15141094 | Fennell TR, Snyder RW, Parkinson C, Murphy J, James RA: The effect of ethylene exposure on ethylene oxide in blood and on hepatic cytochrome p450 in Fischer rats. Toxicol Sci. 2004 Sep;81(1):7-13. Epub 2004 May 12. It is metabolized to ethylene oxide (EO) by cytochrome P450. |
41(0,1,2,6) | Details |
| 17287153 | Deng G, Lin DQ, Yao SJ, Mei LH: Aqueous micellar two-phase system composed of hyamine-type hydrophobically modified ethylene oxide and application for cytochrome P450 BM-3 separation. J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Jun 1;852(1-2):167-73. Epub 2007 Jan 13. |
32(0,1,1,2) | Details |
| 16870169 | Munter T, Cottrell L, Ghai R, Golding BT, Watson WP: The metabolism and molecular toxicology of chloroprene. Chem Biol Interact. 2007 Mar 20;166(1-3):323-31. Epub 2006 Jun 3. Chloroprene (2-chloro-1,3-butadiene, 1) is oxidised by cytochrome P450 enzymes in mammalian liver microsomes to several metabolites, some of which are reactive towards DNA and are mutagenic. |
2(0,0,0,2) | Details |
| 14976339 | Himmelstein MW, Carpenter SC, Hinderliter PM: Kinetic modeling of beta-chloroprene metabolism: I. Toxicol Sci. 2004 May;79(1):18-27. Epub 2004 Feb 19. Estimates for Vmax and Km for cytochrome P450-dependent oxidation of CD in liver microsomes ranged from 0.068 to 0.29 micromol/h/mg protein and 0.53 to 1.33 microM, respectively. |
1(0,0,0,1) | Details |
| 17263564 | Marsden DA, Jones DJ, Lamb JH, Tompkins EM, Farmer PB, Brown K: Determination of endogenous and exogenously derived N7-(2-hydroxyethyl) adducts in ethylene oxide-treated rats. Chem Res Toxicol. 2007 Feb;20(2):290-9. Epub 2007 Jan 31. It is also formed endogenously as a result of cytochrome P450-mediated metabolism of ethylene, which is ubiquitous in the environment. |
1(0,0,0,1) | Details |