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Havel J, Patocka J, Bocaz G: Determination of physostigmine and pyridostigmine in pharmaceutical formulations by capillary electrophoresis. J Capill Electrophor Microchip Technol. 2002 Sep-Dec;7(5-6):107-12.
Physostigmine (PHY) and pyridostigmine (PYR) are two important anticholinesterase compounds with several clinical uses.
The optimal separation conditions for PHY were: 50 mM boric acid-HCl buffer (pH 3.25) with 30 mM NaClO4, electrokinetic injection for 5 sec at -5 kV, temperature 25 degrees C, and separation voltage 15 kV. |
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