| Name | chloride channel (protein family or complex) |
|---|---|
| Synonyms | chloride channel |
| Name | fenpropathrin |
|---|---|
| CAS | cyano(3-phenoxyphenyl)methyl 2,2,3,3-tetramethylcyclopropanecarboxylate |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19766671 | Breckenridge CB, Holden L, Sturgess N, Weiner M, Sheets L, Sargent D, Soderlund DM, Choi JS, Symington S, Clark JM, Burr S, Ray D: Evidence for a separate mechanism of toxicity for the Type I and the Type II pyrethroid insecticides. Neurotoxicology. 2009 Nov;30 Suppl 1:S17-31. Epub 2009 Sep 18. Four of six alpha-cyano pyrethroids (lambda-cyfluthrin, cypermethrin, deltamethrin and fenpropathrin) reduced open chloride channel probability. |
82(1,1,1,2) | Details |
| 17603033 | Borg JJ, Hancox JC, Zhang H, Spencer CI, Li H, Kozlowski RZ: Differential pharmacology of the cardiac anionic background current I (AB). Eur J Pharmacol. 2007 Aug 27;569(3):163-70. Epub 2007 Jun 5. This study investigated the effects of on I (AB) of four pyrethroid agents tefluthrin (a selective activator of this current), tetramethrin, fenpropathrin and alpha-cypermethrin in addition to other well known chloride channel modulators (chlorotoxin, gadolinium and picrotoxin). |
31(0,1,1,1) | Details |
| 14657519 | Burr SA, Ray DE: Structure-activity and interaction effects of 14 different pyrethroids on voltage-gated ion channels. Toxicol Sci. 2004 Feb;77(2):341-6. Epub 2003 Dec 2. It therefore appears clear that in some combinations the type I and type II pyrethroids can compete and may bind to the same chloride channel target site. For single dosing at 10 microM, bioallethrin, beta-cyfluthrin, cypermethrin, deltamethrin, and fenpropathrin were all found to significantly decrease open channel probability (p < 0.05). |
1(0,0,0,1) | Details |