Protein Information

Name Acetylcholinesterase
Synonyms ACHE; ACHE protein; AChE; ARACHE; AcChoEase; Acetylcholine acetylhydrolase; Acetylcholinesterase; Acetylcholinesterase isoform E4 E6 variant…

Compound Information

Name silica gel
CAS silica gel

Reference List

PubMed Abstract RScore(About this table)
19166722 Mroczek T, Mazurek J: Pressurized liquid extraction and anticholinesterase activity-based thin-layer chromatography with bioautography of Amaryllidaceae alkaloids. Anal Chim Acta. 2009 Feb 9;633(2):188-96. Epub 2008 Nov 30.


Quantitative results were obtained by both HPTLC-densitometry on silica gel plates and RP-HPLC with diode array (DAD) on XTerra C (18) stationary phase.
0(0,0,0,0) Details
16076434 Suwansa-ard S, Kanatharana P, Asawatreratanakul P, Limsakul C, Wongkittisuksa B, Thavarungkul P: Semi disposable reactor biosensors for detecting carbamate pesticides in water. Biosens Bioelectron. 2005 Sep 15;21(3):445-54. Epub 2004 Dec 21.

Acetylcholinesterase was immobilized on silica gel by covalent binding. pH and conductivity electrodes were used to detect the ionic change of the sample solution due to hydrolysis of acetylcholine.
32(0,1,1,2) Details
20146521 Fujiwara M, Yagi N, Miyazawa M: Acetylcholinesterase inhibitory activity of volatile oil from Peltophorum dasyrachis Kurz ex Bakar (yellow batai) and Bisabolane-type sesquiterpenoids. J Agric Food Chem. 2010 Mar 10;58(5):2824-9.

The main characteristic constituent in P. dasyrachis was isolated by silica gel column chromatography and found to be a sesquiterpenoid, (+)-(S)-ar-turmerone (1).
7(0,0,0,7) Details
15911323 Andrade MT, Lima JA, Pinto AC, Rezende CM, Carvalho MP, Epifanio RA: Indole alkaloids from Tabernaemontana australis (Muell. Bioorg Med Chem. 2005 Jun 2;13(12):4092-5.

Arg) Miers that inhibit acetylcholinesterase enzyme..
Of these, the first four were isolated by silica gel open column chromatography, identified by uni- and bidimensional NMR, IR, MS and showed anti-cholinesterasic activity at the same concentration as the reference compounds physostigmine and galanthamine (detection limit of 0.01mM) by TLC assay using the modified Ellman's method.
1(0,0,0,1) Details