Protein Information

Name Tyrosinase
Synonyms LB24 AB; Monophenol monooxygenase; OCA1A; OCAIA; SK29 AB; TYR; TYR protein; Tumor rejection antigen AB…

Compound Information

Name silica gel
CAS silica gel

Reference List

PubMed Abstract RScore(About this table)
19685748 Piao X: [Tyrosinase inhibitor from Angelica dahurica roots] . Zhongguo Zhong Yao Za Zhi. 2009 May;34(9):1117-20.

METHOD: A tyrosinase inhibitory constituent was isolated by silica gel column chromatography combined with a bioassay-linked HPLC method.
87(1,1,1,7) Details
19586602 Ding HY, Lin HC, Chang TS: Tyrosinase inhibitors isolated from the roots of Paeonia suffruticosa. J Cosmet Sci. 2009 May-Jun;60(3):347-52.

Six tyrosinase inhibitors were isolated by ethanol extraction, n-hexane, ethyl acetate, n-BuOH, and water partition, silica gel column chromatography, Sephadex LH-20, Lobar PR-8, and high-performance liquid chromatography methods, and they were identified as kaempferol (I), quercetin (II), mudanpioside B (III), benzoyloxypaeoniflorin (IV), mudanpioside H (V), and pentagalloyl-beta-(D)-glucose (VI) on the basis of spectroscopic evidence.
34(0,1,1,4) Details
16676120 Cho YH, Kim JH, Park SM, Lee BC, Pyo HB, Park HD: New cosmetic agents for skin whitening from Angelica dahurica. J Cosmet Sci. 2006 Jan-Feb;57(1):11-21.

In order to find the active constituents from this plant, the ethanol extracts were chromatographed repeatedly with silica gel.
They significantly inhibited tyrosinase synthesis in B16 melanoma cells.
3(0,0,0,3) Details
19294375 Kang J, Kim YM, Kim N, Kim DW, Nam SH, Kim D: Synthesis and characterization of hydroquinone fructoside using Leuconostoc mesenteroides levansucrase. Appl Microbiol Biotechnol. 2009 Jul;83(6):1009-16. Epub 2009 Mar 18.

The product was purified using 1-butanol partition and silica-gel column chromatography.
HQ-Fru showed anti-oxidation activities and inhibition against tyrosinase.
2(0,0,0,2) Details