Protein Information

Name acetylcholine receptors (protein family or complex)
Synonyms Acetylcholine receptor; Acetylcholine receptors

Compound Information

Name fenoxycarb
CAS

Reference List

PubMed Abstract RScore(About this table)
14644616 Smulders CJ, Bueters TJ, Van Kleef RG, Vijverberg HP: Selective effects of carbamate pesticides on rat neuronal nicotinic acetylcholine receptors and rat brain acetylcholinesterase. Toxicol Appl Pharmacol. 2003 Dec 1;193(2):139-46.

Comparing the potencies of inhibition of the distinct subtypes of nicotinic acetylcholine receptors shows that the alpha3beta2 receptor is less sensitive to inhibition by fenoxycarb and EPTC.
33(0,1,1,3) Details
15329441 Smulders CJ, Van Kleef RG, de Groot A, Gotti C, Vijverberg HP: A noncompetitive, sequential mechanism for inhibition of rat alpha4beta2 neuronal nicotinic acetylcholine receptors by carbamate pesticides. Toxicol Sci. 2004 Nov;82(1):219-27. Epub 2004 Aug 25.

Carbaryl, S-ethyl N,N-dipropylthiocarbamate (EPTC), and fenoxycarb inhibit ACh-induced ion currents in a concentration-dependent way.
1(0,0,0,1) Details