| 19966042 |
Takeuchi H, Kubota S, Murakashi E, Zhou Y, Endo K, Ng PS, Takigawa M, Numabe Y: Nicotine-induced CCN2: from smoking to periodontal fibrosis. . J Dent Res. 2010 Jan;89(1):34-9. Epub .
Interestingly, 1 microg/mL nicotine increased the production of CCN2/CTGF protein in both cells without increasing mRNA expression. |
137(1,2,6,7) |
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| 19481023 |
Khanna AK, Xu J, Baquet C, Mehra MR: Adverse effects of nicotine and immunosuppression on proximal tubular epithelial cell viability, tissue repair and oxidative stress gene expression. J Heart Lung Transplant. 2009 Jun;28(6):612-20. Epub 2009 May 5.
Compared with control, treatment of PTE cells with N increased mRNA expression of transforming growth factor-beta (TGF-beta; 10-fold), connective tissue growth factor (CTGF; 25-fold), osteopontin (OPN; 10-fold) and NADPH oxidase components (p22 (phox), NOX-1 and Rac-1 at 18-, 16- and 12-fold, respectively). |
1(0,0,0,1) |
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