| Name | alpha synuclein |
|---|---|
| Synonyms | Alpha synuclein; PARK4; PD1; NACP; Non A beta component of AD amyloid; Non A4 component of amyloid; Non A4 component of amyloid precursor; PARK 1… |
| Name | nicotine |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19013262 | Hong DP, Fink AL, Uversky VN: Smoking and Parkinson's disease: does nicotine affect alpha-synuclein fibrillation?. Biochim Biophys Acta. 2009 Feb;1794(2):282-90. Epub 2008 Oct 25. We show that nicotine and inhibit alpha-synuclein fibril formation in a concentration-dependent manner, with nicotine being more effective. |
176(2,2,4,6) | Details |
| 19075704 | Ono K, Hirohata M, Yamada M: Alpha-synuclein assembly as a therapeutic target of Parkinson's disease and related disorders. Curr Pharm Des. 2008;14(30):3247-66. Recently, various compounds such as nicotine and wine-related polyphenols have been reported to inhibit the formation of falphaS, and to destabilize preformed falphaS at pH 7.5 at 37 degrees C in vitro. |
3(0,0,0,3) | Details |