| Name | alkaline phosphatase |
|---|---|
| Synonyms | ALP 1; Alkaline phosphatase; ALPG; ALPPL; ALPPL 2; ALPPL2; GCAP; Germ cell alkaline phosphatase… |
| Name | nicotine |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19436947 | Rothem DE, Rothem L, Soudry M, Dahan A, Eliakim R: Nicotine modulates bone metabolism-associated gene expression in osteoblast cells. J Bone Miner Metab. 2009;27(5):555-61. Epub 2009 May 13. To identify possible mechanisms underlying nicotine-induced changes in osteogenic metabolism, we defined changes in proliferation and osteocalcin, type I collagen, and alkaline phosphatase gene expression after treating human osteosarcoma cells (MG63), with various concentration of nicotine. |
87(1,1,2,2) | Details |
| 19546357 | Zhou YB, Jin SJ, Cai Y, Teng X, Chen L, Tang CS, Qi YF: Lanthanum inhibits vascular calcification induced by plus nicotine in rats. Exp Biol Med. 2009 Aug;234(8):908-17. Epub 2009 Jun 22. As compared with control rats, rats with calcification showed widespread calcified nodules and irregular elastic fibers in calcified aorta on von Kossa staining and increased aortic and contents, alkaline phosphatase (ALP) activity and bone-related protein expressions for osteopontin (OPN) and type III dependent cotransporter Pit-1 (Pit-1). |
1(0,0,0,1) | Details |
| 20209193 | Pereira ML, Carvalho JC, Peres F, Fernandes MH: Simultaneous effects of nicotine, acrolein, and on osteogenic-induced bone marrow cells cultured on plasma-sprayed titanium implants. Int J Oral Maxillofac Implants. 2010 Jan-Feb;25(1):112-22. Results: Acrolein and caused dose-dependent inhibitory effects at levels similar to and greater than 0.03 and 0.1 mmol/L, respectively; IC50 regarding cell viability/proliferation and alkaline phosphatase was 0.06 mmol/L for acrolein and 0.3 mmol/L for |
1(0,0,0,1) | Details |
| 19468831 | Reddy BV, Sundari JS, Balamurugan E, Menon VP: Prevention of nicotine and streptozotocin treatment induced circulatory oxidative stress by bis-1,7-(2-hydroxyphenyl)-hepta-1,6-diene-3,5-dione in diabetic rats. Mol Cell Biochem. 2009 Nov;331(1-2):127-33. Epub 2009 May 26. Efficacy of BDMCA was determined by evaluating blood thiobarbituric acid reactive substances (TBARS), hydroperoxides (HP), activities of marker enzymes alkaline phosphatase (ALP), and lactate dehydrogenase (LDH) and activities of antioxidant enzymes superoxide dismutase (SOD), catalase (CAT) and peroxidase (GPx). |
1(0,0,0,1) | Details |
| 19656028 | Lee HJ, Pi SH, Kim Y, Kim HS, Kim SJ, Kim YS, Lee SK, Kim EC: Effects of nicotine on antioxidant defense enzymes and RANKL expression in human periodontal ligament cells. J Periodontol. 2009 Aug;80(8):1281-8. RESULTS: Nicotine treatment concomitantly downregulated the expression of OPG and osteoblastic differentiation markers, such as alkaline phosphatase, osteocalcin, and osteopontin, and upregulated the expression of RANKL. |
6(0,0,1,1) | Details |
| 19927714 | Bai B, Zhong LF, Zhu JT: [Nicotine affects biological properties of the human osteosarcoma cell line MG63]. Hua Xi Kou Qiang Yi Xue Za Zhi. 2009 Oct;27(5):483-6. The alkaline phosphatase (ALP) activity was estimated by PNPP. |
1(0,0,0,1) | Details |
| 19910445 | Cai Y, Xu MJ, Teng X, Zhou YB, Chen L, Zhu Y, Wang X, Tang CS, Qi YF: Intermedin inhibits vascular calcification by increasing the level of matrix gamma-carboxyglutamic acid protein. Cardiovasc Res. 2010 Mar 1;85(4):864-73. Epub 2009 Nov 12. VDN-treated rat aortas showed lower IMD content and increased expression of its receptors, along with increased vascular calcium deposition and alkaline phosphatase (ALP) activity. |
1(0,0,0,1) | Details |
| 19766150 | Liu Y, Zhou YB, Zhang GG, Cai Y, Duan XH, Teng X, Song JQ, Shi Y, Tang CS, Yin XH, Qi YF: Cortistatin attenuates vascular calcification in rats. Regul Pept. 2010 Jan 8;159(1-3):35-43. Epub . In this study, we investigated in rats whether CST inhibits vascular calcification induced by and nicotine treatment in vivo and calcification of cultured rat vascular smooth muscular cells (VSMCs) induced by beta-glycerophosphate in vitro and the underlying mechanism. We measured rat hemodynamic variables, alkaline phosphatase (ALP) activity, calcium deposition and pathological changes in aortic tissues and cultured VSMCs. |
1(0,0,0,1) | Details |