| Name | Ghrelin |
|---|---|
| Synonyms | Appetite regulating hormone; Appetite regulating hormone precursor; GHRL; Ghrelin; Growth hormone releasing peptide; Growth hormone secretagogue; M46 protein; MTLRP… |
| Name | nicotine |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19247191 | Hu CZ, Cao YL, Huo HY, Zhao WH, Hu J: Inhibitory effect of ghrelin on nicotine-induced VCAM-1 expression in human umbilical vein endothelial cells. J Cardiovasc Pharmacol. 2009 Mar;53(3):241-5. Our study showed that ghrelin inhibited nicotine-induced VCAM-1 expression in human umbilical vein endothelial cells in a concentration-dependent and time-dependent way. |
288(3,4,6,8) | Details |
| 19892939 | Horn CC, Still L, Fitzgerald C, Friedman MI: Food restriction, refeeding, and gastric fill fail to affect emesis in musk shrews. Am J Physiol Gastrointest Liver Physiol. 2009 Nov 5. Reports indicate that ghrelin and endocannabinoids, agents that stimulate appetite, also reduce emesis evoked by chemotherapy treatment, which suggests that stimulation of feeding inhibits the emetic system. Emesis was induced in musk shrews, a commonly used animal model for emesis research, using the cancer chemotherapy agent cisplatin (20 mg/kg, ip), nicotine (2 mg/kg, sc), or motion (1 Hz, horizontal, 4 cm displacement), because these treatments are known to target separate emetic pathways: gut vagal afferents, area postrema, and vestibular pathways, respectively. |
1(0,0,0,1) | Details |
| 19766150 | Liu Y, Zhou YB, Zhang GG, Cai Y, Duan XH, Teng X, Song JQ, Shi Y, Tang CS, Yin XH, Qi YF: Cortistatin attenuates vascular calcification in rats. Regul Pept. 2010 Jan 8;159(1-3):35-43. Epub . Further, growth hormone-releasing peptide-6 [D-lys], the endogenous antagonist of GHSR1a, markedly reversed the increased ALP activity and calcium deposition in VSMCs. In this study, we investigated in rats whether CST inhibits vascular calcification induced by and nicotine treatment in vivo and calcification of cultured rat vascular smooth muscular cells (VSMCs) induced by beta-glycerophosphate in vitro and the underlying mechanism. |
1(0,0,0,1) | Details |