Protein Information

Name leptin
Synonyms LEP; Leptin; Leptin precursor; OB; OBS; Obese protein; Obesity factor; leptin (murine obesity homolog)…

Compound Information

Name nicotine
CAS

Reference List

PubMed Abstract RScore(About this table)
19828259 von der Goltz C, Koopmann A, Dinter C, Richter A, Rockenbach C, Grosshans M, Nakovics H, Wiedemann K, Mann K, Winterer G, Kiefer F: Orexin and leptin are associated with nicotine craving: a link between smoking, appetite and reward. Psychoneuroendocrinology. 2010 May;35(4):570-7. Epub 2009 Oct 13.
70(0,2,3,5) Details
19067528 Swislocki AL, Fakiri Z: Smokeless nicotine exposure has no lasting effect on fasting or postglucose circulation leptin in young rats. Metab Syndr Relat Disord. 2008 Winter;6(4):257-62.

We used a smokeless tobacco model to study leptin responses to nicotine or placebo treatment.
14(0,0,2,4) Details
19380255 Wang W, Baghdoyan HA, Lydic R: Leptin replacement restores supraspinal cholinergic antinociception in leptin-deficient obese mice. J Pain. 2009 Aug;10(8):836-43. Epub 2009 Apr 19.

The PRF was injected with neostigmine, carbachol, nicotine, N (6)-p-sulfophenyladenosine (SPA), morphine, or saline (control), and latency to paw withdrawal (PWL) from a thermal stimulus was recorded.
6(0,0,0,6) Details
20190011 Oliveira E, Pinheiro C, Santos-Silva A, Trevenzoli I, Abreu-Villaca Y, Nogueira Neto J, Reis A, Passos M, Moura E, Lisboa P: Nicotine exposure affects mother's and pup's nutritional, biochemical and hormonal profiles during lactation in rats. J Endocrinol. 2010 Feb 26.

The 15 days-old NIC-pups presented higher total body fat, higher HDL-cholesterol, serum leptin, serum corticosterone and adrenal catecholamine content, but lower tyrosine hydroxylase protein levels.
1(0,0,0,1) Details
19171179 Delbro D, Westerlund A, Bjorklund U, Hansson E: In inflammatory reactive astrocytes co-cultured with brain endothelial cells nicotine-evoked Ca (2+) transients are attenuated due to interleukin-1beta release and rearrangement of actin filaments. Neuroscience. 2009 Mar 17;159(2):770-9. Epub 2009 Jan 9.

0(0,0,0,0) Details