Protein Information

Name Myosin
Synonyms Myosin

Compound Information

Name rotenone
CAS

Reference List

PubMed Abstract RScore(About this table)
19196822 Marin-Corral J, Minguella J, Ramirez-Sarmiento AL, Hussain SN, Gea J, Barreiro E: Oxidised proteins and superoxide anion production in the diaphragm of severe COPD patients. Eur Respir J. 2009 Jun;33(6):1309-19. Epub 2009 Feb 5.

In severe COPD patients compared with controls, respiratory muscle function was impaired; creatine kinase, carbonic anhydrase III, actin and myosin were oxidised; myosin carbonylation levels were increased five-fold; creatine kinase content and activity and myosin protein were reduced; superoxide anion levels were increased in both mitochondria and membrane compartments; and the percentage of superoxide anion inhibition achieved by rotenone was significantly greater.
31(0,1,1,1) Details
8135534 Kabakov AE, Gabai VL: Stress-induced insolubilization of certain proteins in ascites tumor cells. Arch Biochem Biophys. 1994 Mar;309(2):247-53.


The transient ATP deprivation alone (without protein denaturation) induced a rapid insolubilization of myosin that was the earliest manifestation of ATP deficiency in the cells.
2(0,0,0,2) Details
19137683 Samoilov VO, Bigdai EV, Rudenko IaN, Bekusova VV, Dudich BA: [Two molecular motility systems of the frog olfactory cilia] . Biofizika. 2008 Nov-Dec;53(6):993-9.

The motility of olfactory cilia of frog (Rana temporaria) was studied by vital video microscopy under an exposure to odorants: pentanol, camphor, cineole, vanillin (first group), ammonia, and hydrogen sulfide (second group) as well as inhibitors of cell respiration (rotenone and malonate).
It was shown that olfactory cilia have both a dynein-tubulin and an actin-myosin molecular motility system.
1(0,0,0,1) Details
11964372 Sward K, Dreja K, Lindqvist A, Persson E, Hellstrand P: Influence of mitochondrial inhibition on global and local [Ca (2+)](I) in rat tail artery. Circ Res. 2002 Apr 19;90(7):792-9.


In the rat tail artery, mitochondrial inhibitors (rotenone, antimycin A, and cyanide) reduced alpha (1)-adrenoceptor-stimulated force by 50% to 80%, but did not reduce global [Ca (2+)](i).
0(0,0,0,0) Details