Name | brains |
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Synonyms | BPG dependent PGAM 1; Brain; CDABP0006; PGAM 1; PGAM B; PGAM1; PGAM1 protein; PGAMA… |
Name | lindane |
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CAS | (1α,2α,3β,4α,5α,6β)-1,2,3,4,5,6-hexachlorocyclohexane |
PubMed | Abstract | RScore(About this table) | |
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9600388 | Brannen KC, Devaud LL, Liu J, Lauder JM: Prenatal exposure to neurotoxicants dieldrin or lindane alters tert-butylbicyclophosphorothionate binding to (A) receptors in fetal rat brainstem. Dev Neurosci. 1998;20(1):34-41. Effects of daily prenatal exposure to organochlorine insecticide (dieldrin or lindane) or bicuculline from embryonic day (E) 12-17 were determined in brains of E17 fetal rats using t-[35S] butyl-bicyclophosphorothionate ([35S] TBPS) binding. |
31(0,1,1,1) | Details |
18695515 | Mao H, Liu B: Synergistic microglial reactive lindane and dieldrin. Neuroreport. 2008 Aug 27;19(13):1317-20. We report here that lindane and dieldrin, two widely present OCPs that are found enriched in the nigra of postmortem Parkinson's disease brains synergistically induced the production of reactive species (ROS) in microglia. |
species generation induced by pesticides 31(0,1,1,1) | Details |
1701514 | Serrano MT, Vendrell M, Rivera S, Serratosa J, Rodriguez-Farre E: Effect of lindane on the myelination process in the rat. Neurotoxicol Teratol. 1990 Nov-Dec;12(6):577-83. Furthermore, the immunohistochemical study of brains by means of a MBP (myelin basic protein) specific antibody reveals myelin deficits in some brain regions after lindane treatment. |
6(0,0,1,1) | Details |
7517654 | Fleming L, Mann JB, Bean J, Briggle T, Sanchez-Ramos JR: Parkinson's disease and brain levels of organochlorine pesticides. Ann Neurol. 1994 Jul;36(1):100-3. Dieldrin was detected in 6 of 20 PD brains, 1 of 7 AD, and in none of 14 control samples. |
2(0,0,0,2) | Details |
1702501 | Martinez E, de Vera N, Artigas F: Differential response of rat brain polyamines to convulsant agents. Life Sci. 1991;48(1):77-84. Kainic acid (10 mg/kg), picrotoxinin (1.5 mg/kg), pentylenetetrazol (60 mg/kg) and lindane (gamma-hexachlorocyclohexane) (60 mg/kg) were given to male Wistar rats. Twenty-four hours later, the animals were sacrificed and their brains removed. |
1(0,0,0,1) | Details |
11329709 | Ulrich EM, Willett KL, Caperell-Grant A, Bigsby RM, Hites RA: Understanding enantioselective processes: a laboratory rat model for alpha-hexachlorocyclohexane accumulation. Environ Sci Technol. 2001 Apr 15;35(8):1604-9. Since cyclodextrin gas chromatography columns became popular for chiral separations, many researchers have noticed high enantiomeric ratios [ER: (+)-enantiomer/(-)-enantiomer] for alpha-HCH in the brains of wildlife. |
1(0,0,0,1) | Details |
19597089 | Richardson JR, Shalat SL, Buckley B, Winnik B, O'Suilleabhain P, Diaz-Arrastia R, Reisch J, German DC: Elevated serum pesticide levels and risk of Parkinson disease. . Arch Neurol. 2009 Jul;66(7):870-5. Three studies have found elevated levels of organochlorine pesticides in postmortem PD brains. |
1(0,0,0,1) | Details |