Protein Information

Name neurotoxic esterase
Synonyms NTE; SWS; Neuropathy target esterase; Neurotoxic esterase; PNPLA 6; patatin like phospholipase domain containing 6; Neuropathy target esterases…

Compound Information

Name cyanofenphos
CAS

Reference List

PubMed Abstract RScore(About this table)
7077681 Soliman SA, Linder R, Farmer J, Curley A: Species susceptibility to delayed toxic neuropathy in relation to in vivo inhibition of neurotoxic esterase by neurotoxic organophosphorus esters. J Toxicol Environ Health. 1982 Feb;9(2):189-97.

In the chickens, TOCP and cyanofenphos produced about 98 and 90% in vivo inhibition of brain neurotoxic esterase (NTE) activity.
82(1,1,1,2) Details
2432215 Soliman SA, Curley A, Farmer J, Novak R: In vivo inhibition of chicken brain acetylcholinesterase and neurotoxic esterase in relation to the delayed neurotoxicity of leptophos and cyanofenphos. J Environ Pathol Toxicol Oncol. 1986 Sep-Dec;7(1-2):211-24.
32(0,1,1,2) Details
6084066 Soliman SA, Farmer JD: Delayed neuropathy in adult Peking ducks induced by some organophosphorus esters. J Toxicol Environ Health. 1984;14(5-6):789-801.

Biochemically, it was found that duck brain neurotoxic esterase (NTE) activity was inhibited in vivo to less than 15% of control levels as measured 24 h after the last treatment with TOCP, leptophos, or cyanofenphos.
31(0,1,1,1) Details
6169754 El-Sebae AH, Soliman SA, Ahmed NS, Curley A: Biochemical interaction of six OP delayed neurotoxicants with several neurotargets. J Environ Sci Health B. 1981;16(4):465-74.

Five organophosphorous insecticides: Leptophos, EPN, Cyanofenphos, trichloronate and salithion proved to cause irreversible ataxia not only to chicken but also to mice and sheep.
The six compounds and their oxons were screened for their in-vitro inhibition to monamine oxidase (MAO), acetyl cholinesterase (AChE) and neurotoxic esterase (NTE) in the brain of either mouse, lamb or chicken.
1(0,0,0,1) Details
438464 El-Sebae AH, Soliman SA, Ahmed NS: Delayed neuropathy in sheep by the phosphonothioate insecticide cyanofenphos. J Environ Sci Health B. 1979;14(3):247-63.

In brain samples from ataxiated animals, AChE, MAO and NTE (neurotoxic esterase) activities were assayed simultaneously with untreated animal.
1(0,0,0,1) Details