| Name | neurotoxic esterase |
|---|---|
| Synonyms | NTE; SWS; Neuropathy target esterase; Neurotoxic esterase; PNPLA 6; patatin like phospholipase domain containing 6; Neuropathy target esterases… |
| Name | EPN |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 72768 | El-Sebae AH, Soliman SA, Elamayem MA, Ahmed NS: Neurotoxicity of organophosphorus insecticides Leptophos and EPN. J Environ Sci Health B. 1977;12(4):269-87. The five tested organophosphorus insecticides were compared for their ability to inhibit cholinesterase, neurotoxic esterases and monoamine oxidase. |
2(0,0,0,2) | Details |
| 3629585 | Johnson MK, Read DJ: The influence of chirality on the delayed neuropathic potential of some organophosphorus esters: neuropathic and prophylactic effects of stereoisomeric esters of ethyl phenylphosphonic acid (EPN oxon and EPN) correlate with quantities of aged and unaged neuropathy target esterase in vivo. Toxicol Appl Pharmacol. 1987 Aug;90(1):103-15. |
2(0,0,0,2) | Details |
| 6205472 | Hoffman DJ, Sileo L, Murray HC: Subchronic organophosphorus ester-induced delayed neurotoxicity in mallards. Toxicol Appl Pharmacol. 1984 Aug;75(1):128-36. Brain neurotoxic esterase activity was inhibited by averages of 16, 69, 73, and 74% in the 10-, 30-, 90-, and 270-ppm groups, respectively. |
1(0,0,0,1) | Details |
| 11696925 | Singh AK: QSAR for the organophosphate-induced inhibition and 'aging' of the enzyme neuropathy target esterase (NTE). SAR QSAR Environ Res. 2001;12(3):275-95. The neuropathy-target-esterase (NTE) inhibition data were either obtained from the literature for a number of OP compounds or were determined experimentally for methamidophos, acephate, coumaphos and EPN. |
1(0,0,0,1) | Details |
| 6710528 | Hoffman DJ, Sileo L: and teratogenic effects of an organophosphorus insecticide (phenyl phosphonothioic acid-O-ethyl-O- ester) on mallard development. Toxicol Appl Pharmacol. 1984 Apr;73(2):284-94. Brain neurotoxic esterase (NTE) activity was inhibited by as much as 91% at 11 days, 81% at 18 days, and 79% in hatchlings. |
1(0,0,0,1) | Details |
| 6169754 | El-Sebae AH, Soliman SA, Ahmed NS, Curley A: Biochemical interaction of six OP delayed neurotoxicants with several neurotargets. J Environ Sci Health B. 1981;16(4):465-74. The six compounds and their oxons were screened for their in-vitro inhibition to monamine oxidase (MAO), acetyl cholinesterase (AChE) and neurotoxic esterase (NTE) in the brain of either mouse, lamb or chicken. |
1(0,0,0,1) | Details |
| 2019992 | Abou-Donia MB, Hu ZH, Lapadula DM, Gupta RP: Mechanisms of joint neurotoxicity of n-hexane, methyl isobutyl ketone and O-ethyl O- phenylphosphonothioate in hens. J Pharmacol Exp Ther. 1991 Apr;257(1):282-9. Hen brain acetylcholinesterase and neurotoxic esterase activities were inhibited in hens treated concurrently with EPN, n-hexane and MiBK. |
1(0,0,0,1) | Details |
| 438464 | El-Sebae AH, Soliman SA, Ahmed NS: Delayed neuropathy in sheep by the phosphonothioate insecticide cyanofenphos. J Environ Sci Health B. 1979;14(3):247-63. In brain samples from ataxiated animals, AChE, MAO and NTE (neurotoxic esterase) activities were assayed simultaneously with untreated animal. |
1(0,0,0,1) | Details |
| 6192547 | Soliman SA, Svendsgaard D, Farmer JD, Curley A, Durham WF: Six-month daily treatment of sheep with organophosphorus compounds. Toxicol Appl Pharmacol. 1983 Jul;69(3):417-31. These clinical results were supported by histological findings and also by biochemical results with neurotoxic esterase (NTE) measurements. |
1(0,0,0,1) | Details |
| 10321902 | Barber D, Correll L, Ehrich M: Comparative effectiveness of organophosphorus protoxicant activating systems in neuroblastoma cells and brain homogenates. J Toxicol Environ Health A. 1999 May 14;57(1):63-74. The ability of and rat liver microsomes (RLM) to convert organophosphorus (OP) protoxicants to esterase inhibitors was determined by measuring acetylcholinesterase (AChE) and neuropathy target esterase (NTE) inhibition. |
1(0,0,0,1) | Details |