| Name | choline acetyltransferase |
|---|---|
| Synonyms | CHAT; CHOACTase; CLAT; CMS1A; CMS1A2; ChAT; Choline O acetyltransferase; Choline acetylase… |
| Name | HCH |
|---|---|
| CAS | 1,2,3,4,5,6-hexachlorocyclohexane |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 3696497 | Hohmann GF, Wenk GL, Lowenstein P, Brown ME, Coyle JT: Age-related recurrence of basal forebrain lesion-induced cholinergic deficits. Neurosci Lett. 1987 Dec 4;82(3):253-9. Choline acetyltransferase (ChAT) activity and [3H] hemicholinium-3 ([3H] HCh-3) binding are reduced in cortex ipsilateral to ibotenic acid lesions in the 12-month postlesion rat following an initial recovery to normal levels by about 3 months postlesion. |
31(0,1,1,1) | Details |
| 2626444 | Sweeney JE, Puttfarcken PS, Coyle JT: Galanthamine, an acetylcholinesterase inhibitor: a time course of the effects on performance and neurochemical parameters in mice. Pharmacol Biochem Behav. 1989 Sep;34(1):129-37. Galanthamine concentrations up to 1 x 10 (-5) M did not affect choline acetyltransferase (ChAT) activity, [3H] hemicholinium-3 (HCh-3) binding to the carrier, [3H] quinuclidinylbenzilate (QNB) binding to muscarinic receptors, or [3H] binding to nicotinic receptors in cortical homogenates. |
0(0,0,0,0) | Details |
| 4075090 | Sandberg K, Coyle JT: Characterization of [3H] hemicholinium-3 binding associated with neuronal uptake sites in rat brain membranes. Brain Res. 1985 Dec 2;348(2):321-30. Hemicholinium-3 (HCh-3) is a potent and specific inhibitor of the high-affinity transport process (HAChT) localized on cholinergic neurons. |
0(0,0,0,0) | Details |