Protein Information

Name IFNG
Synonyms IFG; IFI; IFN gamma; IFNG; IFNgamma; Immune interferon; Interferon gamma; Interferon gamma precursor…

Compound Information

Name chlordane
CAS

Reference List

PubMed Abstract RScore(About this table)
1456175 Theus SA, Tabor DR, Soderberg LS, Barnett JB: Macrophage tumoricidal mechanisms are selectively altered by prenatal chlordane exposure. Agents Actions. 1992 Sep;37(1-2):140-6.

In this study, m phi from chlordane-treated animals required a 48 h in vitro period of induction with interferon-gamma and lipopolysaccharide (IFN/LPS) before they could kill P815 targets.
31(0,1,1,1) Details
19066394 Colt JS, Rothman N, Severson RK, Hartge P, Cerhan JR, Chatterjee N, Cozen W, Morton LM, De Roos AJ, Davis S, Chanock S, Wang SS: Organochlorine exposure, immune gene variation, and risk of non-Hodgkin lymphoma. Blood. 2009 Feb 26;113(9):1899-905. Epub 2008 Dec 9.

We examined 3 exposures with elevated risk in this study: PCB180 (plasma, dust measurements), the toxic equivalency quotient (an integrated functional measure of several organochlorines) in plasma, and alpha-chlordane (dust measurements, self-reported termiticide use).
Associations between all 3 exposures and NHL risk were limited to the same genotypes for IFNG (C-1615T) TT and IL4 (5'-UTR, Ex1-168C> T) CC.
1(0,0,0,1) Details