Protein Information

Name GABA at
Synonyms (S) 3 amino 2 methylpropionate transaminase; 4 aminobutyrate aminotransferase; ABAT; ABAT protein; GABA aminotransferase; GABA transaminase; GABA AT; GABA T…

Compound Information

Name alpha-endosulfan
CAS (3α,5aβ,6α,9α,9aβ)-6,7,8,9,10,10-hexachloro-1,5,5a,6,9,9a-hexahydro-6,9-methano-2,4,3-benzodioxathiepin 3-oxide

Reference List

PubMed Abstract RScore(About this table)
7885191 Cole LM, Roush RT, Casida JE: Drosophila GABA-gated chloride channel: modified [3H] EBOB binding site associated with Ala--> Ser or Gly mutants of Rdl subunit. Life Sci. 1995;56(10):757-65.

This specific binding of [3H] EBOB is strongly inhibited by: a large number and variety of insecticidal channel blockers at 20 nM (lindane, alpha-endosulfan, dieldrin, 12-ketoendrin, fipronil, and a representative bicycloorthobenzoate and dithiane) or 200 nM (picrotoxinin); the insecticidal channel activators avermectin and moxidectin at 20 nM; muscimol at 30 microM and GABA at 300 microM.
81(1,1,1,1) Details