| Name | dopamine transporter |
|---|---|
| Synonyms | DA transporter; DAT1; DAT; DAT 1; Dopamine transporter; SLC6A3; Sodium dependent dopamine transporter; Dopamine transporters… |
| Name | heptachlor |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 10499361 | Miller GW, Kirby ML, Levey AI, Bloomquist JR: Heptachlor alters expression and function of dopamine transporters. . Neurotoxicology. 1999 Aug;20(4):631-7. |
112(1,2,2,2) | Details |
| 11719704 | Purkerson-Parker S, McDaniel KL, Moser VC: Dopamine transporter binding in the rat striatum is increased by gestational, perinatal, and adolescent exposure to heptachlor. Toxicol Sci. 2001 Dec;64(2):216-23. |
112(1,2,2,2) | Details |
| 16112329 | Caudle WM, Richardson JR, Wang M, Miller GW: Perinatal heptachlor exposure increases expression of presynaptic dopaminergic markers in mouse striatum. Neurotoxicology. 2005 Aug;26(4):721-8. Studies from our laboratory and others have demonstrated that exposure of laboratory animals to heptachlor alters the levels and function of the dopamine transporter (DAT), an integral component of dopaminergic neurotransmission and a gateway for the dopaminergic neurotoxin MPTP. |
81(1,1,1,1) | Details |
| 12428726 | Bloomquist JR, Barlow RL, Gillette JS, Li W, Kirby ML: Selective effects of insecticides on nigrostriatal dopaminergic nerve pathways. Neurotoxicology. 2002 Oct;23(4-5):537-44. Western blot analysis confirmed increased levels of dopamine transporter (DAT) protein in the striatum of mice treated with heptachlor and permethrin. |
6(0,0,1,1) | Details |
| 18577399 | Richardson JR, Caudle WM, Wang MZ, Dean ED, Pennell KD, Miller GW: Developmental heptachlor exposure increases susceptibility of neurons to N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in a gender-specific manner. Neurotoxicology. 2008 Sep;29(5):855-63. Epub 2008 Jun 5. Exposure of pregnant mice to heptachlor led to increased levels of the dopamine transporter (DAT) and vesicular monoamine transporter 2 (VMAT2) levels at both the protein and mRNA level in their offspring. |
6(0,0,1,1) | Details |
| 11294980 | Kirby ML, Barlow RL, Bloomquist JR: Neurotoxicity of the organochlorine insecticide heptachlor to murine striatal dopaminergic pathways. Toxicol Sci. 2001 May;61(1):100-6. Increases in maximal rate of striatal uptake were attributed to induction of the dopamine transporter (DAT) and a compensatory response to elevated synaptic levels of |
1(0,0,0,1) | Details |