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heptachlor

Identification (Source:EPA,EU)

ID	1480
Name	heptachlor
CAS	76-44-8
IUPAC	1,4,5,6,7,8,8-heptachloro-3a,4,7,7a-tetrahydro-4,7-methanoindene
Inchi	InChI=1S/C10H5Cl7/c11-4-2-1-3-5(4)9(15)7(13)6(12)8(3,14)10(9,16)17/h1-5H
CIPAC	36
EPA Code	044801
Formula	C10H5Cl7
SMILES	ClC1(C(Cl)2Cl)C(C=CC3Cl)C3C2(Cl)C(Cl)=C1Cl
Status	Not Approved

Classification

Mode of Action	Persistent, non-systemic contact and stomach poison with some fumigant action. Is a chloride channel-blocking agent.
Pesticide Type	Insecticide
Chemical Group	Organochlorine
Classification	cyclodiene insecticides

Properties (Source:PubChem)

Molecular Weight	373.32
Physical State	White to tan coloured crystals
AlogP	4.24
H-Bond Donor	0
H-Bond Acceptor	0
Surface Area	277.55
Polar Surface Area	0.0

Structure

Ecotoxicology (Source:PPDB,IPM)

Species	Method	Study Time	Dose Type	Value
Algae	Acute	72 hour	EC50, growth	0.027 mg l-1
Aquatic invertebrates	Acute	48 hour	EC50	0.042 mg l-1
Birds	Acute		LD50	2000 mg kg-1
Fish	Acute	96 hour	LC50	0.007 mg l-1
Honeybees	Acute	48 hour	LD50	128.5 μg bee-1
Mammals	Acute oral		LD50	147 mg kg-1
Mammals	Short term dietary		NOEL	5 ppm diet
	Bio-concentration factor		CT50	Not available days
	Bio-concentration factor		BCF	7400

Related targets

Target Name	RScore (About this table)
dopamine transporter	318(3,5,7,8)	Details
ERK1	244(3,3,3,4)	Details
U82	236(2,4,6,6)	Details
GABA receptor (protein family or complex)	204(2,3,4,9)	Details
mitogen activated protein kinase (protein family or complex)	200(2,3,4,5)	Details
MC7	217(1,5,7,7)	Details
CPP32	125(1,2,4,5)	Details
c jun	118(1,2,3,3)	Details
ERK2	112(1,2,2,2)	Details
cytochrome b5	99(1,1,2,14)	Details
MC 2	94(1,1,3,4)	Details
bcl 2	87(1,1,2,2)	Details
benzodiazepine receptor (protein family or complex)	87(1,1,2,2)	Details
serine threonine kinases	82(1,1,1,2)	Details
phospholipase C	81(1,1,1,1)	Details
TGFbeta	81(1,1,1,1)	Details
thrombin	81(1,1,1,1)	Details
vesicular monoamine transporter 2	84(0,2,5,9)	Details
novel protein	63(0,2,2,3)	Details
cytochrome P450 (protein family or complex)	68(0,1,4,23)	Details
protein kinase C (protein family or complex)	54(0,1,4,9)	Details
Connexin 43	44(0,1,2,9)	Details
U83	37(0,1,2,2)	Details
ErbB 2	34(0,1,1,4)	Details
cytochrome P450 reductase	34(0,1,1,4)	Details
cytochrome c	33(0,1,1,3)	Details
MEK1	32(0,1,1,2)	Details
PC 3	31(0,1,1,1)	Details
MEKK	31(0,1,1,1)	Details
HEPT	55(0,0,8,15)	Details
estrogen receptor	18(0,0,1,13)	Details

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