Protein Information

Name phospholipase C
Synonyms PLC L; PLCE; PLC L (PLC epsilon); PLCL; PLCL 1; PLCL1; PLDL 1; PLDL1…

Compound Information

Name heptachlor
CAS

Reference List

PubMed Abstract RScore(About this table)
12242688 Moya de Juri MG, Magnarelli De Potas G, Pechen de D'Angelo AM: Alteration of thrombine-signaling mechanism by heptachlor in human platelets. J Biochem Mol Toxicol. 2002;16(4):189-96.

We propose that signal transduction steps downstream phospholipase C (PLC) are unphysiologically activated by heptachlor and facilitated by the increase in phosphatidylinositolbiphosphate, the substrate for PLC activity, thus producing an accumulation of phosphatidic acid.
81(1,1,1,1) Details