| Name | cytochrome c |
|---|---|
| Synonyms | CYC; CYCS; Cytochrome C; HCS; Cytochrome Cs |
| Name | 1-naphthol |
|---|---|
| CAS | 1-naphthalenol |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 3240719 | Jagadeesan V, Oesch F: Effects of dietary zinc deficiency on the activity of enzymes associated with phase I and II of drug metabolism in Fischer-344 rats: activities of drug metabolising enzymes in zinc deficiency. Drug Nutr Interact. 1988;5(4):403-13. It was observed that the activities of microsomal epoxide hydrolase (with benz (a) pyrene 4-5 oxide as substrate), diphospho glucuronyl transferase (with 1-naphthol as substrate) and cytosolic glutathione-S-transferase (with chlorodinitrobenzene as substrate) were altered exclusively due to zinc deficiency. There was a change in the activities of the following enzymes, which could be due either to zinc deficiency and/or food restriction: 1) aryl hydrocarbon hydroxylase; 2) cytochrome b; 3) cytochrome c; and 4) cytochrome b5. |
1(0,0,0,1) | Details |
| 2820596 | Eastmond DA, French RC, Ross D, Smith MT: Metabolic activation of 1-naphthol and by a simple -generating system and human leukocytes. Chem Biol Interact. 1987;63(1):47-62. In contrast, the addition of 1-naphthol to PMA-stimulated neutrophils interfered with -dependent cytochrome c reduction as well as luminol-dependent chemiluminescence and also resulted in protein binding. |
81(1,1,1,1) | Details |
| 13866943 | BELMAN S, TROLL W: The interaction of 2-amino-1-naphthol with bovine serum albumin and cytochrome c in relation to its effect on rat bladder. J Biol Chem. 1962 Mar;237:746-50. |
31(0,1,1,1) | Details |
| 6431226 | Mackenzie PI, Lang MA, Owens IS: Effect of different detergent systems on the molecular size of UDP glucuronosyltransferase and other microsomal drug-metabolizing enzymes. Membr Biochem. 1984;5(3):193-207. Mouse liver microsomes were solubilized in various detergent systems, and the resulting aggregate structures associated with cytochrome P-450, cytochrome c reductase, and UDP glucuronosyltransferase were sized by gel filtration chromatography. CHAPS alone also generated similarly sized particles under conditions in which UDP glucuronosyltransferase activity toward 1-naphthol and morphine was two to about twenty times greater, respectively, than with the combination of detergents. |
2(0,0,0,2) | Details |
| 6768341 | Pardini RS, Heidker JC, Baker TA, Payne B: Toxicology of various pesticides and their decomposition products on mitochondrial electron transport. Arch Environ Contam Toxicol. 1980;9(1):87-97. DDT, DDE and TDE, dihydroxynaphthalene and 1-naphthol inhibited the -oxidase enzyme system onthe substrate side of cytochrome c, whereas Kelthane inhibited on the side. |
1(0,0,0,1) | Details |
| 7948817 | Desmond PV, Smyth FE, Mashford ML: Release of latent glucuronosyltransferase activity contributes to the sparing of glucuronidation in experimental liver injuries. J Gastroenterol Hepatol. 1994 Jul-Aug;9(4):350-4. This study explores the effects of liver injuries induced in rats by the administration of acute carbon tetrachloride, chronic bile duct ligation and chronic choline deficiency for 30 weeks on the glucuronidation of and 1-naphthol, both before and after solubilization of the microsomes and compares this to three measures of oxidation. Cytochrome C reductase fell to 58 and 32% of control and hydroxylase to 46 and 13%, respectively, after acute carbon tetrachloride and bile duct ligation. |
1(0,0,0,1) | Details |
| 14738905 | Nebbia C, Dacasto M, Carletti M: Postnatal development of hepatic oxidative, hydrolytic and conjugative drug-metabolizing enzymes in female horses. Life Sci. 2004 Feb 13;74(13):1605-19. Rather unexpectedly, both the CYP content and the activity of cytochrome c reductase rose as a function of age. Also the carboxylesterases and uridindiphosphoglucuronyl-transferase (UGT) activity toward 1-naphthol displayed a similar trend, glutathione S-transferase accepting 3,4-dichloronitrobenzene as a substrate being the only enzyme activity showing an age-related decline. |
1(0,0,0,1) | Details |