| Name | N acetyltransferase |
|---|---|
| Synonyms | AAC 2; NAT2; AAC2; ARY 2; ARY2; Arylamide acetylase 2; Arylamine N acetyltransferase 2; N acetyltransferase… |
| Name | 1-naphthol |
|---|---|
| CAS | 1-naphthalenol |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 10895755 | Chen TL, Wu CH, Chen TG, Tai YT, Chang HC, Lin CJ: Effects of propofol on functional activities of hepatic and extrahepatic conjugation enzyme systems. Br J Anaesth. 2000 Jun;84(6):771-6. The functional activities of phase-II enzymes, including -glucuronosyltransferase (UDPGT), glutathione S-transferase (GST) and N-acetyltransferase (NAT) were evaluated in the presence of various concentrations of propofol (0.05-1.0 mmol litre-1), using 1-naphthol, 1-chloro-2,4-dinitrobenzene and as substrates respectively. |
31(0,1,1,1) | Details |
| 14508638 | Birkner S, Weber S, Dohle A, Schmahl G, Bolt HM, Follmann W: Activities of drug metabolizing enzymes in bovine colon epithelial cell cultures. Arch Toxicol. 2003 Nov;77(11):621-9. Epub 2003 Sep 24. Whereas activity of amino sulfotransferase (substrate 2-naphthylamine) decreased continuously during the entire culture period, the activity of phenol sulfotransferase (substrate 1-naphthol) decreased only slowly. To examine phase II metabolic potency, activities of N-acetyltransferases 1 and 2, of and amino sulfotransferases, of glutathione S-transferases alpha, mu, pi and theta and of UDP-glucuronyltransferase were measured. |
2(0,0,0,2) | Details |
| 8870952 | Guhe C, Degen GH, Schuhmacher US, Kiefer F, Follmann W: Drug metabolizing enzyme activities in porcine urinary bladder epithelial cell cultures (PUBEC). Arch Toxicol. 1996;70(10):599-606. N-acetyltransferase (NAT) activity measured with a diagnostic substrate for human NAT-1, was stable and even higher during the culture period compared to freshly isolated cells. A similar decline was also observed for UDP-glucuronyltransferase activities measured with 1-naphthol. |
1(0,0,0,1) | Details |