Protein Information

Name glial fibrillary acidic protein
Synonyms GFAP; Glial fibrillary acidic protein; Glial fibrillary acidic proteins

Compound Information

Name 1-naphthol
CAS 1-naphthalenol

Reference List

PubMed Abstract RScore(About this table)
2412992 Mauro A, Germano I, Giaccone G, Giordana MT, Schiffer D: 1-Naphthol basic dye (1-NBD). Histochemistry. 1985;83(2):97-102.

The usefulness of 1-naphthol as substrate for horseradish peroxidase (HRP) in immunohistochemistry was studied using the peroxidase-antiperoxidase (PAP) and avidin-biotin-complex (ABC) methods in the demonstration of glial fibrillary acidic protein (GFAP), vimentin, carbonic anhydrase C (CA.C), and factor VIII-related antigen (FVIII/RAg) in central nervous tissue and cerebral tumors.
87(1,1,2,2) Details
1707903 Castellano B, Gonzalez B, Jensen MB, Pedersen EB, Finsen BR, Zimmer J: A double staining technique for simultaneous demonstration of astrocytes and microglia in brain sections and astroglial cell cultures. J Histochem Cytochem. 1991 May;39(5):561-8.

Finally, in a series of intervening steps, the NDPase reaction product was visualized and stabilized by treatment with ammonium sulfide and silver nitrate, while the 1-naphthol basic dye method was used to visualize the GFAP immunoreactive product.
35(0,1,1,5) Details
2765300 Takemoto O, Yoshimine T, Hayakawa T, Fujita T, Nakajima S, Taneda M, Mogami H: [Astrocytic proliferation in the brain adjacent to infarcted lesion: immunohistochemical study of astroprotein (GFAP) and bromodeoxyuridine (BrdU)]. No To Shinkei. 1989 Apr;41(4):361-5.

Double-labeled immunohistochemical technique (avidin biotin peroxidase-complex method) was carried out with each antibody using 3,3'-diaminobenzidine tetrahydrochloride and 4-chloro-1-naphthol as chromogens.
4(0,0,0,4) Details