| Name | leptin |
|---|---|
| Synonyms | LEP; Leptin; Leptin precursor; OB; OBS; Obese protein; Obesity factor; leptin (murine obesity homolog)… |
| Name | ACC |
|---|---|
| CAS | 1-aminocyclopropanecarboxylic acid |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19956534 | Sakar Y, Nazaret C, Letteron P, Ait Omar A, Avenati M, Viollet B, Ducroc R, Bado A: Positive regulatory control loop between gut leptin and intestinal GLUT2/GLUT5 transporters links to hepatic metabolic functions in rodents. PLoS One. 2009 Nov 30;4(11):e7935. |
8(0,0,0,8) | Details |
| 18255222 | Janovska A, Hatzinikolas G, Staikopoulos V, McInerney J, Mano M, Wittert GA: AMPK and ACC phosphorylation: effect of leptin, muscle fibre type and obesity. Mol Cell Endocrinol. 2008 Mar 12;284(1-2):1-10. Epub 2008 Jan 3. |
8(0,0,0,8) | Details |
| 19698760 | Roman EA, Reis D, Romanatto T, Maimoni D, Ferreira EA, Santos GA, Torsoni AS, Velloso LA, Torsoni MA: Central leptin action improves skeletal muscle AKT, AMPK, and PGC1 alpha activation by hypothalamic PI3K-dependent mechanism. Mol Cell Endocrinol. 2010 Jan 15;314(1):62-9. Epub 2009 Aug 19. |
7(0,0,0,7) | Details |
| 19394382 | Masuzaki H, Tanaka T, Ebihara K, Hosoda K, Nakao K: Hypothalamic melanocortin signaling and leptin resistance--perspective of therapeutic application for obesity-diabetes syndrome. Peptides. 2009 Jul;30(7):1383-6. Epub 2009 Apr 23. |
7(0,0,0,7) | Details |
| 17956983 | Gao S, Kinzig KP, Aja S, Scott KA, Keung W, Kelly S, Strynadka K, Chohnan S, Smith WW, Tamashiro KL, Ladenheim EE, Ronnett GV, Tu Y, Birnbaum MJ, Lopaschuk GD, Moran TH: Leptin activates hypothalamic carboxylase to inhibit food intake. Proc Natl Acad Sci U S A. 2007 Oct 30;104(44):17358-63. Epub 2007 Oct 23. |
6(0,0,0,6) | Details |
| 19052642 | Ropelle ER, Fernandes MF, Flores MB, Ueno M, Rocco S, Marin R, Cintra DE, Velloso LA, Franchini KG, Saad MJ, Carvalheira JB: Central exercise action increases the AMPK and mTOR response to leptin. . PLoS One. 2008;3(12):e3856. Epub 2008 Dec 4. |
6(0,0,0,6) | Details |
| 17488641 | Tanaka T, Masuzaki H, Yasue S, Ebihara K, Shiuchi T, Ishii T, Arai N, Hirata M, Yamamoto H, Hayashi T, Hosoda K, Minokoshi Y, Nakao K: Central melanocortin signaling restores skeletal muscle AMP-activated protein kinase phosphorylation in mice fed a high-fat diet. Cell Metab. 2007 May;5(5):395-402. Skeletal muscle AMP-activated protein kinase (AMPK) is activated by leptin and serves as a master regulator of fatty acid beta-oxidation. |
3(0,0,0,3) | Details |
| 19717488 | Fuentes T, Ara I, Guadalupe-Grau A, Larsen S, Stallknecht B, Olmedillas H, Santana A, Helge JW, Calbet JA, Guerra B: Leptin receptor 170 kDa (OB-R170) protein expression is reduced in obese human skeletal muscle: a potential mechanism of leptin resistance. Exp Physiol. 2010 Jan;95(1):160-71. Epub 2009 Aug 28. |
3(0,0,0,3) | Details |
| 19100718 | Rivera L, Moron R, Zarzuelo A, Galisteo M: Long-term administration reduces metabolic disturbances and lowers blood pressure in obese Zucker rats. Biochem Pharmacol. 2009 Mar 15;77(6):1053-63. Epub 2008 Dec 3. The high plasma concentrations of triglycerides, total free fatty acids, insulin and leptin found in obese Zucker rats were reduced in obese rats that received |
1(0,0,0,1) | Details |
| 19500808 | Chen CH, Chang MY, Lin YS, Lin DG, Chen SW, Chao PM: A herbal extract with carboxylase inhibitory activity and its potential for treating metabolic syndrome. Metabolism. 2009 Sep;58(9):1297-305. Epub 2009 Jun 18. After 4 weeks, body weight and levels of blood insulin, triacylglycerol, total and leptin were significantly reduced (P < .05) in mice fed a 3% EP-containing HF diet. |
1(0,0,0,1) | Details |
| 18314006 | Pang J, Choi Y, Park T: Ilex paraguariensis extract ameliorates obesity induced by high-fat diet: potential role of AMPK in the visceral adipose tissue. Arch Biochem Biophys. 2008 Aug 15;476(2):178-85. Epub 2008 Feb 26. I. paraguariensis extract supplementation significantly lowered body weight, visceral fat-pad weights, blood and hepatic lipid, insulin, and leptin levels of rats administered HFD. |
1(0,0,0,1) | Details |