| Name | cis 3 |
|---|---|
| Synonyms | ATOD 4; ATOD4; CIS 3; CIS3; Cish3; Cytokine inducible SH2 protein 3; SOCS 3; SOCS3… |
| Name | 1,3-dichloropropene |
|---|---|
| CAS | 1,3-dichloro-1-propene |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 8243412 | Osterloh JD, Feldman BJ: Urinary protein markers in pesticide applicators during a chlorinated hydrocarbon exposure. Environ Res. 1993 Nov;63(2):171-81. A previous study of 16 pesticide applicators showed that N-acetylglucosaminidase (NAG) excretion during exposure to the soil nematocide, 1,3-dichloropropene (DCP), was correlated with DCP dose and the excretion of its major metabolite, N-acetyl-S-(cis-3-chloroprop-2-enyl)- (3CNAC). |
81(1,1,1,1) | Details |
| 19856961 | Robertson BA, Schroeder GK, Jin Z, Johnson KA, Whitman CP: Pre-steady-state kinetic analysis of cis-3-chloroacrylic acid dehalogenase: analysis and implications. Biochemistry. 2009 Dec 15;48(49):11737-44. These reactions represent key steps in the degradation of the nematocide, 1,3-dichloropropene. |
2(0,0,0,2) | Details |
| 9687453 | Poelarends GJ, Wilkens M, Larkin MJ, van Elsas JD, Janssen DB: Degradation of 1,3-dichloropropene by pseudomonas cichorii 170. Appl Environ Microbiol. 1998 Aug;64(8):2931-6. This organism produced at least three different dehalogenases: a hydrolytic haloalkane dehalogenase specific for haloalkanes and two 3-chloroacrylic acid dehalogenases, one specific for cis-3-chloroacrylic acid and the other specific for trans-3-chloroacrylic acid. |
2(0,0,0,2) | Details |
| 15381403 | Poelarends GJ, Whitman CP: Evolution of enzymatic activity in the tautomerase superfamily: mechanistic and structural studies of the 1,3-dichloropropene catabolic enzymes. Bioorg Chem. 2004 Oct;32(5):376-92. The characterization of three enzymes in these pathways, trans-3-chloroacrylic acid dehalogenase (CaaD), cis-3-chloroacrylic acid dehalogenase (cis-CaaD), and decarboxylase (MSAD), has uncovered intriguing catalytic mechanisms as well as a fascinating evolutionary lineage for these proteins. |
1(0,0,0,1) | Details |
| 2313738 | Osterloh J, He XW: Effects of 1,3-dichloropropene on the kidney of Fisher 344 rats after pretreatment with diethyl buthionine sulfoximine, and aminooxyacetic acid. J Toxicol Environ Health. 1990;29(3):247-55. Excretion of protein, N-acetylglucosaminidase (NAG), and the major metabolite of DCP, N-acetyl-S-(cis-3-chloroprop-2-enyl)- (3CNAC), was measured. |
1(0,0,0,1) | Details |
| 17121835 | de Jong RM, Bazzacco P, Poelarends GJ, Johnson WH Jr, Kim YJ, Burks EA, Serrano H, Thunnissen AM, Whitman CP, Dijkstra BW: Crystal structures of native and inactivated cis-3-chloroacrylic acid dehalogenase. J Biol Chem. 2007 Jan 26;282(4):2440-9. Epub 2006 Nov 22. The bacterial degradation pathways for the nematocide 1,3-dichloropropene rely on hydrolytic dehalogenation reactions catalyzed by cis- and trans-3-chloroacrylic acid dehalogenases (cis-CaaD and CaaD, respectively). |
1(0,0,0,1) | Details |
| 10616720 | Katsivela E, Bonse D, Kruger A, Strompl C, Livingston A, Wittich RM: An extractive membrane biofilm reactor for degradation of 1,3-dichloropropene in industrial waste water. Appl Microbiol Biotechnol. 1999 Nov;52(6):853-62. EK1 uzilizes cis-3-chloroallylalcohol and cis-3-chloroacrylic acid, whereas the metabolite trans-3-chloroacrylic acid represents a dead-end product of the pathway of this strain. |
1(0,0,0,1) | Details |
| 11024197 | Brouwer EJ, Verplanke AJ, Boogaard PJ, Bloemen LJ, Van Sittert NJ, Christian FE, Stokkentreeff M, Dijksterhuis A, Mulder A, De Wolff FA: Personal air sampling and biological monitoring of occupational exposure to the soil fumigant cis-1,3-dichloropropene. Occup Environ Med. 2000 Nov;57(11):738-44. The metabolite N-acetyl-S-(cis-3-chloro-2-propenyl)- (cis-DCP-MA) in urine was used for biological monitoring of the cis-DCP uptake. |
1(0,0,0,1) | Details |
| 19277287 | Ou LT, Chung KY, Thomas JE, Obreza TA, Dickson DW: Degradation of 1,3-dichloropropene (1,3-d) in soils with different histories of field applications of 1,3-d. J Nematol. 1995 Sep;27(3):249-57. |
0(0,0,0,0) | Details |