Protein Information

Name protein is
Synonyms ANX 2; p36; LIP 2; LIP2; ANX2; ANX2L4; ANX2P1; ANX2P2…

Compound Information

Name IAA
CAS

Reference List

PubMed Abstract RScore(About this table)
16903352 Padmanabhan MS, Shiferaw H, Culver JN: The Tobacco mosaic virus replicase protein disrupts the localization and function of interacting Aux/IAA proteins. Mol Plant Microbe Interact. 2006 Aug;19(8):864-73.


In this study, the TMV replicase protein is shown to colocalize with IAA26 in the cytoplasm and prevent its accumulation within the nucleus.
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18604494 Da Mota FF, Gomes EA, Seldin L: Auxin production and detection of the gene coding for the Auxin Efflux Carrier (AEC) protein in Paenibacillus polymyxa. J Microbiol. 2008 Jun;46(3):257-64. Epub 2008 Jul 5.


This is the first study to demonstrate that the AEC protein is present in P. polymyxa genome.
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18042668 Rafii M, McKenzie JM, Roberts SA, Steiner G, Ball RO, Pencharz PB: In vivo regulation of phenylalanine hydroxylation to tyrosine, studied using enrichment in apoB-100. Am J Physiol Endocrinol Metab. 2008 Feb;294(2):E475-9. Epub 2007 Nov 27.


Studies of in vivo regulation of phenylalanine hydroxylation suffer from the lack of a method to determine intrahepatocyte enrichment of phenylalanine and tyrosine. apoB-100, a hepatic export protein, is synthesized from intrahepatocyte amino acids.
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16430864 Ge SM, Xie BE, Chen SF: Characterization of two trpE genes encoding anthranilate synthase alpha-subunit in Azospirillum brasilense. Biochem Biophys Res Commun. 2006 Mar 10;341(2):494-9. Epub 2006 Jan 13.


The anthranilate synthase assays with trpE1 (G)- and trpE2- mutants demonstrated that TrpE1 (G) fusion protein is feedback inhibited by tryptophan while TrpE2 protein is not.
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12472684 Park JY, Kim HJ, Kim J: Mutation in domain II of IAA1 confers diverse auxin-related phenotypes and represses auxin-activated expression of Aux/IAA genes in steroid regulator-inducible system. Plant J. 2002 Dec;32(5):669-83.


Auxin induction of Aux/IAA genes in the presence of cycloheximide can be repressed by DEX treatment, showing that the repression of transcription of the Aux/IAAs by the iaa1 mutant protein is primary.
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15546359 Yang X, Lee S, So JH, Dharmasiri S, Dharmasiri N, Ge L, Jensen C, Hangarter R, Hobbie L, Estelle M: The IAA1 protein is encoded by AXR5 and is a substrate of SCF (TIR1). Plant J. 2004 Dec;40(5):772-82.

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19116728 Cosio C, Vuillemin L, De Meyer M, Kevers C, Penel C, Dunand C: An anionic class III peroxidase from zucchini may regulate hypocotyl elongation through its auxin oxidase activity. Planta. 2009 Mar;229(4):823-36. Epub 2009 Jan 1.


We confirmed that the protein is localized near the cell wall, mainly produced in the elongation area of the hypocotyls and respond to exogenous auxin.
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18363780 Negi S, Ivanchenko MG, Muday GK: Ethylene regulates lateral root formation and auxin transport in Arabidopsis thaliana. Plant J. 2008 Jul;55(2):175-87. Epub 2008 Mar 19.


The aux1-7 mutant, which has a defect in an IAA influx protein, is insensitive to the ethylene inhibition of root formation. aux1-7 also has ACC-insensitive acropetal and basipetal IAA transport, as well as altered DR5-GUS expression, which is consistent with ethylene altering AUX1-mediated IAA uptake, and thereby blocking lateral root formation.
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15828683 Vande Broek A, Gysegom P, Ona O, Hendrickx N, Prinsen E, Van Impe J, Vanderleyden J: Transcriptional analysis of the Azospirillum brasilense indole-3-pyruvate decarboxylase gene and identification of a cis-acting sequence involved in auxin responsive expression. Mol Plant Microbe Interact. 2005 Apr;18(4):311-23.


Database searches revealed that the second gene of this operon, named iaaC, is well conserved evolutionarily and that the encoded protein is homologous to the Escherichia coli protein SCRP-27A, the zebrafish protein ES1, and the human protein KNP-I/GT335 (HES1), all of unknown function and belonging to the DJ-1/PfpI superfamily.
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16192309 Vieten A, Vanneste S, Wisniewska J, Benkova E, Benjamins R, Beeckman T, Luschnig C, Friml J: Functional redundancy of PIN proteins is accompanied by auxin-dependent cross-regulation of PIN expression. Development. 2005 Oct;132(20):4521-31.


This regulatory switch is indicative of a mechanism by which the loss of a specific PIN protein is compensated for by auxin-dependent ectopic expression of its homologues.
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9342315 Kim J, Harter K, Theologis A: Protein-protein interactions among the Aux/IAA proteins. Proc Natl Acad Sci U S A. 1997 Oct 28;94(22):11786-91.

Deletion analysis of PS-IAA4 indicates that the betaalphaalpha containing acidic C terminus of the protein is necessary for homotypic interactions in the yeast two-hybrid system.
Screening an Arabidopsis lambda-ACT cDNA library using IAA1 as a bait reveals heterotypic interactions of IAA1 with known and newly discovered members of the Arabidopsis Aux/IAA gene family.
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