Protein Information

Name IL 4
Synonyms B cell differentiation factor gamma; B cell growth factor; B cell stimulatory factor 1; BCDF gamma; BCDFg; BCDFgamma; BCGF; BSF 1…

Compound Information

Name IAA
CAS

Reference List

PubMed Abstract RScore(About this table)
14965001 Popova VV, Mel'nichenko SV, Lukashova RG, Man'kovskii BI, Zak KP: [Content of different cytokines in the blood of healthy children and their siblings who are either.positive or negative for diabetes-associated autoantibodies (GADA, 1A-2A, IAA)]. Lik Sprava. 2003 Dec;(8):26-9.

Content of different cytokines (IF alpha, TNF alpha, IL-1 alpha, IL-4, IL-6 and IL-10) was examined in the blood serum in two groups of healthy children-siblings with type 1 diabetes mellitus with and without revealed insulin autoantibodies against pancreatic islets (GADA, IA-2A and IAA) by enzyme-like immunosorbent assay (ELISA).
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18241652 Li RJ, Qiu SD, Chen HX, Wang LR: [Immunomodulatory effects of Astragalus polysaccharide in diabetic mice] . Zhong Xi Yi Jie He Xue Bao. 2008 Feb;6(2):166-70.


The levels of cytokine interferon-gamma (IFN-gamma) and interleukin-4 (IL-4) secreted by splenocytes were determined by enzyme linked immunosorbent assay (ELISA) method, and the expression of peroxisome proliferator-activated receptor gamma (PPARgamma) in spleens was characterized using Western-blot analysis.
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15093559 Schmid S, Koczwara K, Schwinghammer S, Lampasona V, Ziegler AG, Bonifacio E: Delayed exposure to wheat and barley proteins reduces diabetes incidence in non-obese diabetic mice. Clin Immunol. 2004 Apr;111(1):108-18.


Insulin autoantibodies (P < 0.01) and insulitis scores (P < 0.02) were reduced, and intra-pancreatic IL-4 mRNA increased (P < 0.05) in wheat and barley protein-deprived mice.
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