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David KC, Brady MT, Weimer LK, Hellberg MR, Nixon JC, Graff G: Characterization of the in vitro anti-inflammatory activity of AL-5898 and related benzopyranyl esters and amides. Inflammation. 2003 Feb;27(1):31-43.
Concentration-dependent inhibition of inflammatory cytokine production (i.e., IL-1beta, TNF-alpha, GM-CSF and IL-6) was also apparent in LPS-stimulated, cultured PBMC as well as in PMA/A (23187) activated U-937 cells monitoring the synthesis of IL-1beta, IL-8, TNF-alpha, and MCP-1. |
2(0,0,0,2) |
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