Protein Information

Name interleukin 4
Synonyms B cell differentiation factor gamma; B cell growth factor; B cell stimulatory factor 1; BCDF gamma; BCDFg; BCDFgamma; BCGF; BSF 1…

Compound Information

Name bioallethrin
CAS

Reference List

PubMed Abstract RScore(About this table)
9860237 Diel F, Detscher M, Schock B, Ennis M: In vitro effects of the pyrethroid S-bioallethrin on lymphocytes and basophils from atopic and nonatopic subjects. Allergy. 1998 Nov;53(11):1052-9.

The regulatory interleukin-4/interferon-gamma (JL-4/IFN-gamma) balance showed a significant difference between atopic and nonatopic subjects after a short-term culture period (24 h) in the presence of the same concentration range of S-bioallethrin (P < 0.001).
6(0,0,1,1) Details
12755381 Diel F, Horr B, Borck H, Irman-Florjanc T: Pyrethroid insecticides influence the signal transduction in T helper lymphocytes from atopic and nonatopic subjects. Inflamm Res. 2003 Apr;52(4):154-63.

Only fenvalerate and S-bioallethrin combined with 10-fold PBO in the atopic-enriched blood basophil incubates caused a weak but significant increase in histamine release.
RESULTS: We demonstrated that interferon-gamma (IFN-gamma) production and expression was correlated with lymphocyte proliferation, however, interleukin-4 (IL-4) was down-regulated at the end of the 3 day culture.
3(0,0,0,3) Details
10414782 Diel F, Horr B, Borck H, Savtchenko H, Mitsche T, Diel E: Pyrethroids and piperonyl-butoxide affect human T-lymphocytes in vitro. Toxicol Lett. 1999 Jun 30;107(1-3):65-74.

The regulatory IL-4/IFN-gamma balance showed a significant difference between atopic and non-atopic subjects after a culture period of 24-48 h in the presence of micromolar S-bioallethrin (P < 0.001).
7(0,0,1,2) Details