Protein Information

Name ERF1
Synonyms C11 protein; RF1; ERF1; Cl1 protein; D5S1995; ERF; ETF 1; ETF1…

Compound Information

Name jasmonic acid
CAS

Reference List

PubMed Abstract RScore(About this table)
15242170 Berrocal-Lobo M, Molina A: Ethylene response factor 1 mediates Arabidopsis resistance to the soilborne fungus Fusarium oxysporum. Mol Plant Microbe Interact. 2004 Jul;17(7):763-70.

Expression of ERF1 was upregulated after inoculation with F. oxysporum f. sp. conglutinans, and this response was blocked in ein2-5 and coi1-1 mutants, impaired in the ethylene (ET) and jasmonic acid (JA) signal pathways, respectively, which further indicates that ERF1 is a downstream component of ET and JA defense responses.
33(0,1,1,3) Details
18567832 Asamizu E, Shimoda Y, Kouchi H, Tabata S, Sato S: A positive regulatory role for LjERF1 in the nodulation process is revealed by systematic analysis of nodule-associated transcription factors of Lotus japonicus. Plant Physiol. 2008 Aug;147(4):2030-40. Epub 2008 Jun 20.

We identified a gene, LjERF1, that is most similar to Arabidopsis ERF1, which is up-regulated by ethylene and jasmonic acid and activates downstream defense genes.
32(0,1,1,2) Details
15784880 Stepanova AN, Alonso JM: Arabidopsis ethylene signaling pathway. Sci STKE. 2005 Mar 22;2005(276):cm4.

The coregulation of ERF1 by another plant hormone, jasmonic acid, illustrates how a transcriptional cascade could be utilized in a combinatorial fashion to generate a large diversity of responses using a limited number of input signals.
7(0,0,1,2) Details
17114278 Onate-Sanchez L, Anderson JP, Young J, Singh KB: AtERF14, a member of the ERF family of transcription factors, plays a nonredundant role in plant defense. Plant Physiol. 2007 Jan;143(1):400-9. Epub 2006 Nov 17.

Moreover, the expression of other ERF genes involved in defense and ET/jasmonic acid responses, such as ERF1 and AtERF2, depends on AtERF14 expression.
6(0,0,1,1) Details
12509529 Lorenzo O, Piqueras R, Sanchez-Serrano JJ, Solano R: ETHYLENE RESPONSE FACTOR1 integrates signals from ethylene and jasmonate pathways in plant defense. Plant Cell. 2003 Jan;15(1):165-78.


Here, we show that ethylene and jasmonate pathways converge in the transcriptional activation of ETHYLENE RESPONSE FACTOR1 (ERF1), which encodes a transcription factor that regulates the expression of pathogen response genes that prevent disease progression.
5(0,0,0,5) Details
16822015 Diaz J, Alvarez-Buylla ER: A model of the ethylene signaling pathway and its gene response in Arabidopsis thaliana: pathway cross-talk and noise-filtering properties. Chaos. 2006 Jun;16(2):023112.

We postulate a continuous model of the activation dynamics of the ethylene response factor 1 (ERF1) gene in response to ethylene signaling.
This activation elicits the response of the plant defensin 1 (PDF1) gene, which also responds to jasmonic acid, and the inhibition of the putative auxin responsive factor 2 (ARF2) gene, that also responds to auxin.
3(0,0,0,3) Details
12060224 Berrocal-Lobo M, Molina A, Solano R: Constitutive expression of ETHYLENE-RESPONSE-FACTOR1 in Arabidopsis confers resistance to several necrotrophic fungi. Plant J. 2002 Jan;29(1):23-32.

Infection of a plant by a pathogen induces a variety of defense responses that imply the action of several signaling molecules, including salicylic acid (SA), jasmonic acid (JA) and ethylene (E).
Here we describe the role of ETHYLENE-RESPONSE-FACTOR1 (ERF1) as a regulator of ethylene responses after pathogen attack in Arabidopsis.
2(0,0,0,2) Details
15208388 Lorenzo O, Chico JM, Sanchez-Serrano JJ, Solano R: JASMONATE-INSENSITIVE1 encodes a MYC transcription factor essential to discriminate between different jasmonate-regulated defense responses in Arabidopsis. Plant Cell. 2004 Jul;16(7):1938-50. Epub 2004 Jun 18.


Conversely, Ethylene-Response-Factor1 (ERF1) positively regulates the expression of the first group of genes and represses the second.
2(0,0,0,2) Details
18467450 Pre M, Atallah M, Champion A, De Vos M, Pieterse CM, Memelink J: The AP2/ERF domain transcription factor ORA59 integrates jasmonic acid and ethylene signals in plant defense. Plant Physiol. 2008 Jul;147(3):1347-57. Epub 2008 May 8.

Using two different transient overexpression approaches, we found that only ORA59 and ERF1 were able to activate PDF1.2 gene expression, in contrast to the related proteins AtERF1 and AtERF2.
1(0,0,0,1) Details
16813576 Brodersen P, Petersen M, Bjorn Nielsen H, Zhu S, Newman MA, Shokat KM, Rietz S, Parker J, Mundy J: Arabidopsis MAP kinase 4 regulates salicylic acid- and jasmonic acid/ethylene-dependent responses via EDS1 and PAD4. Plant J. 2006 Aug;47(4):532-46. Epub 2006 Jun 30.

We also show that the MPK4-EDS1/PAD4 branch of ET defense signaling is independent of the ERF1 transcription factor, and use comparative microarray analysis of ctr1, ctr1/mpk4, mpk4 and WT to show that MPK4 is required for induction of a small subset of ET-regulated genes.
1(0,0,0,1) Details
18212027 Wu K, Zhang L, Zhou C, Yu CW, Chaikam V: HDA6 is required for jasmonate response, senescence and flowering in Arabidopsis. J Exp Bot. 2008;59(2):225-34. Epub 2008 Jan 22.


The expression of the jasmonate responsive genes, PDF1.2, VSP2, JIN1, and ERF1, was down-regulated in axe1-5 and HDA6-RNAi plants.
1(0,0,0,1) Details
19928591 Frankowski K, Swiezawska B, Wilmowicz E, Kesy J, Kopcewicz J: [Jasmonate signaling pathway--new insight] . Postepy Biochem. 2009;55(3):337-41.

Significant progress which was made during last few years in research of jasmonic acid signaling pathway yielded surprising information about chemical form of a signaling molecule of the hormone, which turned out to be its conjugate with amino acid isoleucine.
ERF1, WRKY70, MYC2), as well as expression of genes involved in defense responses of plants (i. e.
1(0,0,0,1) Details
19832945 Zander M, La Camera S, Lamotte O, Metraux JP, Gatz C: Arabidopsis thaliana class-II TGA transcription factors are essential activators of jasmonic acid/ethylene-induced defense responses. Plant J. 2010 Jan;61(2):200-10. Epub 2009 Oct 12.

JA/ET induction of the trans-activators ERF1 and ORA59, which act upstream of PDF1.2, was slightly increased (ERF1) or unaffected (ORA59).
1(0,0,0,1) Details
16478936 Liechti R, Gfeller A, Farmer EE: Jasmonate signaling pathway. Sci STKE. 2006 Feb 14;2006(322):cm2.

APETALA2 (AP2)-domain transcription factors, such as ETHYLENE RESPONSE FACTOR 1 (ERF1), link the jasmonate pathway to the ethylene signaling pathway.
As progress in characterizing several new mutants (some of which are hypersensitive to jasmonic acid) augments our understanding of jasmonate signaling, the Connections Map will be updated to include this new information.
1(0,0,0,1) Details
16039901 Lorenzo O, Solano R: Molecular players regulating the jasmonate signalling network. Curr Opin Plant Biol. 2005 Oct;8(5):532-40.


Genes that are involved in the regulation of protein stability through the ubiquitin-proteasome pathway (COI1, AXR1 and SGT1b), signalling proteins (MPK4) and transcription factors (AtMYC2, ERF1, NPR1 and WRKY70) form a regulatory network that allows the plant to fine-tune specific responses to different stimuli.
1(0,0,0,1) Details
17189328 Zarate SI, Kempema LA, Walling LL: Silverleaf whitefly induces salicylic acid defenses and suppresses effectual jasmonic acid defenses. Plant Physiol. 2007 Feb;143(2):866-75. Epub 2006 Dec 22.

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